Results 51 to 60 of about 228,995 (268)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

IKKT thermodynamics and early universe cosmology

Journal of High Energy Physics, 2023
Matrix theory is a proposed non-perturbative definition of superstring theory in which space is emergent. Recently, it was shown that space-time can emerge with a scale-invariant spectrum of cosmological perturbations which is sourced by thermal ...
Samuel Laliberte, Suddhasattwa Brahma
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Interactive Theory of Breastfeeding: creation and application of a middle-range theory

Revista Brasileira de Enfermagem
Objective: To describe a breastfeeding theory based on King's Conceptual System. Method: Theoretical study that used analysis of concept, assertion synthesis, and derivation of theory for the creation of a new theory.
Cândida Caniçali Primo, Marcos Antônio Gomes Brandão   +1 more
doaj   +1 more source

Effective field theory interpretation of lepton magnetic and electric dipole moments

Journal of High Energy Physics, 2021
We perform a model-independent analysis of the magnetic and electric dipole moments of the muon and electron. We give expressions for the dipole moments in terms of operator coefficients of the low-energy effective field theory (LEFT) and the Standard ...
Jason Aebischer, Wouter Dekens, Elizabeth E. Jenkins, Aneesh V. Manohar, Dipan Sengupta, Peter Stoffer   +5 more
doaj   +1 more source

Beyond abstract elementary classes: On the model theory of geometric lattices

Annals of Pure and Applied Logic, 2018
Based on Crapo's theory of one point extensions of combinatorial geometries, we find various classes of geometric lattices that behave very well from the point of view of stability theory. One of them, $(\mathbf{K}^3, \preccurlyeq)$, is $ω$-stable, it has a monster model and an independence calculus that satisfies all the usual properties of non ...
Tapani Hyttinen, Gianluca Paolini
openaire   +3 more sources

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Defects in the tri-critical Ising model

Journal of High Energy Physics, 2017
We consider two different conformal field theories with central charge c = 7/10. One is the diagonal invariant minimal model in which all fields have integer spins; the other is the local fermionic theory with superconformal symmetry in which fields can ...
Isao Makabe, Gérard M.T. Watts
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source