Results 71 to 80 of about 207,997 (268)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

THE OMEGA POINT AS ESCHATON: ANSWERS TO PANNENBERG'S QUESTIONS FOR SCIENTISTS

open access: yesZygon, 1989
. I present an outline of the Omega Point theory, which is a model for an omnipresent, omniscient, omnipotent, evolving, personal God who is both transcendent to spacetime and immanent in it, and who exists necessarily.
doaj   +2 more sources

Supersymmetric SYK model and random matrix theory

open access: yesJournal of High Energy Physics, 2017
In this paper, we investigate the effect of supersymmetry on the symmetry classification of random matrix theory ensembles. We mainly consider the random matrix behaviors in the N = 1 $$ \mathcal{N}=1 $$ supersymmetric generalization of Sachdev-Ye-Kitaev
Tianlin Li   +3 more
doaj   +1 more source

The theorems of beth and Craig in abstract model theory II. Compact logics

open access: yesArchiv für Mathematische Logik und Grundlagenforschung, 1981
Various compact logics such as stationary logic, positive logic, logics with various cardinality quantifiers and cofinality quantifiers are studied. Counterexamples to the theorems of Beth and Craig are given. Back and forth arguments are studied for the first two logics, transfer theorems presented for positive logic and a new compactness proof for ...
Shelah, S., Makowsky, J.A.
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Non-orientable surfaces and electric-magnetic duality

open access: yesJournal of High Energy Physics, 2018
We consider the reduction along two compact directions of a twisted N = 4 gauge theory on a 4-dimensional orientable manifold which is not a global product of two surfaces but contains a non-orientable surface. The low energy theory is a sigma-model on a
Siye Wu
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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