Results 91 to 100 of about 793,519 (318)

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano   +7 more
wiley   +1 more source

A Design Process Framework and Tools for Teaching and Practicing Biomimicry

open access: yesBiomimetics
Few design methods exist that provide clearly structured, visually intuitive, and easily monitored scaffolding for navigating the considerable complexity of biomimetic processes. To this end, we present a holistic biomimicry process framework informed by
Benjamin Linder, Jean Huang
doaj   +1 more source

Improving Abstraction in Text Summarization

open access: yes, 2018
ive text summarization aims to shorten long text documents into a human readable form that contains the most important facts from the original document.
Kryściński, Wojciech   +3 more
core   +1 more source

Cognitive Functioning in Vorinostat‐Treated Pediatric and Young Adult Patients Over the First 180 Days After Hematopoietic Stem Cell Transplant

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Cognitive and psychological difficulties could negatively interfere with treatment adherence and quality of life before and after hematopoietic stem cell transplant (HSCT). Methods to mitigate these changes may have positive effects on treatment success.
Kristen L. Votruba   +11 more
wiley   +1 more source

Aristeus and Thanatos. Samuel Beckett’s Insect Poetics Creepy

open access: yesZoophilologica, 2019
In the broadest possible terms, this paper aims at exploring the relation between death and insects in Samuel Beckett with a special emphasis put on the fact that it is insects that form one of the most repetitive and complex animal figures in his oeuvre.
Michał Kisiel
doaj   +1 more source

Lazy Abstraction-Based Controller Synthesis

open access: yes, 2019
We present lazy abstraction-based controller synthesis (ABCS) for continuous-time nonlinear dynamical systems against reach-avoid and safety specifications.
A Borri   +21 more
core   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm   +10 more
wiley   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi   +4 more
wiley   +1 more source

The Geometry of Thought: Circling Through Concepts

open access: yesPhilosophies
The goal of this paper is to shed light on the nature of mathematical practice, i.e., on “doing mathematics”. It explores Gödel’s perspective, which offers an approach to understanding mathematics centered on concepts, objects, and structures.
Miloš Adžić   +2 more
doaj   +1 more source

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