Results 101 to 110 of about 213,552 (301)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

By their words ye shall know them: Language abstraction and the likeability of describers [PDF]

open access: yes, 2009
According to the linguistic category model (LCM), behaviour can be described at concrete (e.g. ‘Kath hit Kim’) and abstract (e.g. ‘Kath is aggressive’) levels.
Robbie M. Sutton   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

abstraction WE THINKS

open access: yes, 2019
'abstraction WE THINKS' is a group show of Modernist, abstract paintings by artists from the United States and Australia. Co-curated by artists and professors Tim Doud and Zoë Charlton from the collaborative project ‘sindikit’ which was partially ...
McLean, Tarn
core  

Abstraction-Based Data-Driven Control [PDF]

open access: yes, 2022
openOur world is living a paradigm shift in technology policy, often referred to as the Cyber-Physical Revolution or Industry 4.0. Nowadays, Cyber-Physical Systems are ubiquitous in modern control engineering, including automobiles, aircraft, building ...
DE LAZZARI, DAVIDE
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Abstraction as a Tool of Automated Floor-Plan Design

open access: yes, 1986
The automated design of architectural floor plans satisfying given topological and dimensional constraints is a challenging field of research. In this paper ABSTRACTION is pointed out as an important conceptual tool of this field.
P. Galle
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Abstraction: A Historical and Interdisciplinary Perspective

open access: yes, 2013
ion is a pervasive activity in human perception, conceptualization and reasoning; it enters the vocabulary of almost all disciplines, both scientific and humanistic, as well as everyday life.
SAITTA, Lorenza
core  

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