Results 101 to 110 of about 271,263 (249)
KELAM DİLİNİN KURGUSAL NİTELİĞİ-Din-Kelam İlişkisi ve Kelamda Kavramsal Soyutlamanın Zorunluluğu-
A comparision between the religion and kalam from the viewpoint of nature and aim procures to form an opinion about the apperance of kalam and its function which it realized throughout its own history.
Galip Türcan
doaj
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Associate/Dissociate: Allusive and Elusive Care in Veronica Ryan’s Sculpture
Reflecting on the experience of curating Veronica Ryan’s work for the 2021 exhibition Life Support: Forms of Care in Art and Activism at Glasgow Women’s Library, this essay contextualizes the artist’s recent sculptures in relation to the theories ...
Catherine Spencer
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
L’art abstrait du xxe siècle, autour de l’arabesque
Markus Brüderlin
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Shape from dots: a window into abstraction processes in visual perception
IntroductionA remarkable phenomenon in perception is that the visual system spontaneously organizes sets of discrete elements into abstract shape representations.
Nicholas Baker, Philip J. Kellman
doaj +1 more source

