Results 121 to 130 of about 1,557,860 (303)

Diversité spécifique et abondance des communautés de copépodes, cladocères et rotifères des lacs du complexe Ossa (Dizangué, Cameroun)

open access: yesPhysio-Géo, 2012
The composition and the structure of the zooplankton of two lakes of the Ossa lake complex (Ossa and Mwembe) were studied between September 2009 and February 2010.
Joseph Guy Nziéleu Tchapgnouo   +6 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Designing a shipboard line transect survey to estimate cetacean abundance off the Azores Archipelago, Portugal [PDF]

open access: yes, 2009
Revised version November 2008. MRes in Marine Mammal ScienceManagement schemes dedicated to the conservation of wildlife populations rely on the effective monitoring of population size, and this requires the accurate and precise estimation of abundance ...
Faustino, Cláudia Estevinho Santos
core  

The influence of mid-ocean ridges on euphausiid and pelagic ecology [PDF]

open access: yes, 2012
Chapters 1 & 2. Euphausiids comprise a major component of ecosystems in the pelagic realm, the world’s largest habitat, but basin scale drivers of euphausiids diversity and abundance are poorly understood. Mid-Ocean Ridges are the largest topographical
Letessier, Tom Bech
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Supplements to quantitative assessments of zooplankton in the Far Eastern Seas and adjacent waters of the North Pacific

open access: yesИзвестия ТИНРО, 2017
An overview of published and new estimates of zooplankton density and biomass in the Far-Eastern Seas and North-West Pacific with their daily, seasonal and interannual dynamics is presented on the materials of numerous marine expeditions conducted by ...
Vyacheslav P. Shuntov, Igor V. Volvenko
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Density and activity patterns of ocelot populations in Yasuní National Park, Ecuador. [PDF]

open access: yes, 2015
Ocelots were historically hunted for their skins but habitat loss is now their most serious threat, causing rapid declines in populations throughout their range.
Espinosa Andrade, Santiago Rafael
core   +1 more source

DECREASING OF THE PINK SALMON (ONCORHYNCHUS GORBUSCHA) ABUNDANCE IN SAKHALIN-KURIL REGION AS CONSEQUENCE OF EXTREME ENVIRONMENTAL FACTORS IMPACT

open access: yesИзвестия ТИНРО, 2018
The pink salmon abundance dynamics is considered for Sakhalin-Kuril region in 2007–2016. The year-classes of pink salmon originated from Iturup Island and four areas of eastern Sakhalin became weaker if they were affected by typhoons during their ...
A. M. Kaev
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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