Results 131 to 140 of about 3,683,011 (357)

Searching for the signatures of terrestrial planets in F-, G-type main-sequence stars

open access: yes, 2013
We have studied the volatile-to-refractory abundance ratios to investigate their possible relation with the low-mass planetary formation. We present a fully differential chemical abundance analysis using high-quality HARPS and UVES spectra of 61 late F ...
Adibekyan, V. Zh.   +6 more
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Impacts of nitrogen addition on plant species richness and abundance: A global meta‐analysis

open access: yesGlobal Ecology and Biogeography, 2018
Aim: Experimental nitrogen (N) addition (fertilization) studies are commonly used to quantify the impacts of increased N inputs on plant biodiversity. However, given that plant community responses can vary considerably among individual studies, there is ...
G. Midolo   +5 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Two distinct halo populations in the solar neighborhood. Evidence from stellar abundance ratios and kinematics

open access: yes, 2010
Precise abundance ratios are determined for 94 dwarf stars with 5200 < Teff < 6300 K, -1.6 < [Fe/H] < -0.4, and distances D < 335 pc. Most of them have halo kinematics, but 16 thick-disk stars are included.
Carollo   +31 more
core   +3 more sources

Meta-analysis reveals that pollinator functional diversity and abundance enhance crop pollination and yield

open access: yesNature Communications, 2019
How insects promote crop pollination remains poorly understood in terms of the contribution of functional trait differences between species. We used meta-analyses to test for correlations between community abundance, species richness and functional trait
B. Woodcock   +24 more
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Disentangling the abundance–impact relationship for invasive species

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance The shape (linear vs. nonlinear), direction (negative vs. positive), and strength of the relationship between invasive alien species (IAS) abundance and native species diversity determines which invaders present the greatest risk to ...
B. Bradley   +10 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Influence of Cooling Flow and Galactic Motion on the Iron Distribution in Clusters of Galaxies

open access: yes, 1994
Iron abundance distribution is now known for 12 clusters of galaxies. For some clusters (e.g. Centaurus) the observed abundance increases toward the cluster center, while for the others (e.g.
Fujita, Yutaka, Kodama, Hideo
core   +1 more source

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