Results 91 to 100 of about 123,013 (299)

The effect of animal movement on line transect estimates of abundance

, 2015
This work was supported by the University of St Andrews (http://www.st-andrews.ac.uk/; RG, STB, LT) and by a summer scholarship and PhD grant from The Carnegie Trust for the Universities of Scotland (http://www.carnegie-trust.org/) to RG.Line transect ...
Richard Glennie (708832), Stephen T. Buckland (708833), Glennie, R., Thomas, L., Len Thomas, Stephen T Buckland, Stephen T. Buckland, Buckland, S.T., Len Thomas (511985), Richard Glennie   +9 more
core   +1 more source

Abundance and habitat use estimates show Lesser Yellowlegs (Tringa flavipes) breed in high numbers in interior Alaska

Avian Conservation and Ecology, 2022
Lesser Yellowlegs (Tringa flavipes) abundance has declined by approximately 75% across North America since 1970. Despite this dramatic decline, Lesser Yellowlegs are infrequently studied on their breeding grounds and have rarely been studied in the ...
Ellen C. Martin, Paul F. Doherty, Jr., Kim A. Jochum, Calvin F. Bagley   +3 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Estimating Population Abundance Using Sightability Models: R SightabilityModel Package

Journal of Statistical Software, 2012
Sightability models are binary logistic-regression models used to estimate and adjust for visibility bias in wildlife-population surveys (Steinhorst and Samuel 1989).
John R. Fieberg
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Endmember Analysis of Overlapping Handwritten Text in Hyperspectral Document Images

IEEE Access
Hyperspectral Imaging (HSI) uses large portions of the electromagnetic spectrum to obtain information from images that would be very difficult to get otherwise.
Hasan Irtaza Mirza, Saad Bin Ahmed, Roberto Solis-Oba, Muhammad Imran Malik   +3 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Distance software: design and analysis of distance sampling surveys for estimating population size

, 2009
1. Distance sampling is a widely used technique for estimating the size or density of biological populations. Many distance sampling designs and most analyses use the software Distance. 2.
Hedley, S L, Burnham, K P, Buckland, Stephen Terrence, Buckland, Stephen T., Samantha Strindberg, Hedley, Sharon L., Bishop, Jonathan Richard Bryan, Sharon L. Hedley, Marques, Tiago A., Rexstad, Eric, Bishop, J R B, Tiago A. Marques, Kenneth P. Burnham, Eric A. Rexstad, Laake, J L, Burnham, Kenneth P., Rexstad, Eric A, Rexstad, Eric A., Bishop, Jon R.B., Laake, Jeff L., Len Thomas, Jon R.B. Bishop, Marques, Tiago Andre, Jeff L. Laake, Strindberg, S, Strindberg, Samantha, Stephen T. Buckland, Thomas, Len   +27 more
core   +1 more source