Results 71 to 80 of about 485,382 (284)
Knowing the abundance of a population is a crucial component to assess its conservation status and develop effective conservation plans. For most cetaceans, abundance estimation is difficult given their cryptic and mobile nature, especially when the ...
Mats Amundin +32 more
doaj +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Cumberland Sound beluga whale (Delphinapterus leucas) population inhabits Cumberland Sound on the southeast side of Baffin Island, Nunavut. The population is listed as threatened under the Species at Risk Act.
Bryanna A. H. Sherbo +5 more
doaj +1 more source
The mass-metallicity relation of local active galaxies
We systematically measure the gas-phase metallicities and the mass-metallicity relation of a large sample of local active galaxies for the first time.
Dopita, Michael A. +5 more
core +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Distributed Unmixing of Hyperspectral Data With Sparsity Constraint
Spectral unmixing (SU) is a data processing problem in hyperspectral remote sensing. The significant challenge in the SU problem is how to identify endmembers and their weights, accurately. For estimation of signature and fractional abundance matrices in
Khoshsokhan, Sara +2 more
core +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Hybrid mark–resight approaches account for heterogeneous detection bias in aerial surveys
Population abundance estimation is a critical yet challenging task for wildlife management decision‐making. For aerial surveys of terrestrial mammals in highly heterogenous landscapes, estimation models that address multiple sources of detection bias are
Kylie M. Curtis +6 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source

