Results 81 to 90 of about 485,382 (284)

Direct Assessment of Juvenile Atlantic Bluefin Tuna: Integrating Sonar and Aerial Results in Support of Fishery-Incident Surveys [PDF]

, 2014
There is a clear need for direct assessment approaches for Atlantic bluefin tuna (Thunnus thynnus, ABFT), including formulation of experimental designs and pilot surveys for abundance estimation.
Jech, Michael, Lutcavage, E., Rzhanov, Yuri, Vanderlaan, Angelia S.M., Weber, Thomas   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

A catch-free stock assessment model with application to goliath grouper (Epinephelus itajara) off southern Florida [PDF]

, 2006
Many modern stock assessment methods provide the machinery for determining the status of a stock in relation to certain reference points and for estimating how quickly a stock can be rebuilt. However, these methods typically require catch data, which are
Eklund, Anne-Marie, Porch, Clay E., Scott, Gerald P.   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Detection Probability and Bias in Machine-Learning-Based Unoccupied Aerial System Non-Breeding Waterfowl Surveys

Drones
Unoccupied aerial systems (UASs) may provide cheaper, safer, and more accurate and precise alternatives to traditional waterfowl survey techniques while also reducing disturbance to waterfowl.
Reid Viegut, Elisabeth Webb, Andrew Raedeke, Zhicheng Tang, Yang Zhang, Zhenduo Zhai, Zhiguang Liu, Shiqi Wang, Jiuyi Zheng, Yi Shang   +9 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Abundance and habitat use estimates show Lesser Yellowlegs (Tringa flavipes) breed in high numbers in interior Alaska

Avian Conservation and Ecology, 2022
Lesser Yellowlegs (Tringa flavipes) abundance has declined by approximately 75% across North America since 1970. Despite this dramatic decline, Lesser Yellowlegs are infrequently studied on their breeding grounds and have rarely been studied in the ...
Ellen C. Martin, Paul F. Doherty, Jr., Kim A. Jochum, Calvin F. Bagley   +3 more
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Estimation of species relative abundances and habitat preferences using opportunistic data [PDF]

, 2017
We develop a new statistical procedure to monitor, with opportunist data, relative species abundances and their respective preferences for dierent habitat types. Following Giraud et al.
Calenge, Clément, Coron, Camille, Giraud, Christophe, Julliard, Romain   +3 more
core   +2 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source