Results 121 to 130 of about 2,314,115 (247)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Editorial: Assessment Approaches to Support Bycatch Management for Marine Mammals

Frontiers in Marine Science, 2022
André E. Punt, Tessa B. Francis, Tessa B. Francis, Jeffrey E. Moore, Randall R. Reeves   +4 more
doaj   +1 more source

Reliability of trans‐generational genetic mark–recapture (tGMR) for enumerating Pacific salmon

Evolutionary Applications
As Pacific salmon (Oncorhynchus spp.) decline across much of their range, it is imperative to further develop minimally invasive tools to quantify population abundance.
Samuel W. Rosenbaum, Samuel A. May, Kyle R. Shedd, Curry J. Cunningham, Randy L. Peterson, Brian W. Elliot, Megan V. McPhee   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Trade structure and growth [PDF]

Lederman and Maloney examine the empirical relationships between trade structure and economic growth, particularly the influence of natural resource abundance, export concentration, and intra-industry trade.
Maloney, William F., Lederman, Daniel
core  

Using statistical population reconstruction to estimate the effect of pelt prices on river otter abundance and harvest vulnerability in Kentucky

Frontiers in Mammal Science
IntroductionAccurately estimating the abundance, survival rates, and harvest vulnerability of harvested populations of North American river otters (Lontra canadensis) is essential for their effective management and conservation.
Sergey S. Berg, Laura L. Palmer
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Abundance

, 2018
Contains files necessary to recreate analyses of anemone abundance. Bocas_transects_individual_roots.csv contains abundance data for the three sites within the Bocas del Toro archipelago, where anemones were counted on mangrove roots from 30-m transects.
Harilaos Lessios (5162231), Dee Denver (3419306), Reid Edlund (5162225), Bellis, Emily, Edlund, Reid, Hazel Berrios (5162228), Berrios, Hazel, Emily Bellis (3445070), Denver, Dee, Lessios, Harilaos   +9 more
core   +1 more source

Environmental, behavioral, and design-related factors affect accuracy and precision of beluga abundance estimates from aerial surveys

Frontiers in Marine Science
Abundance estimation of wildlife populations is frequently derived from systematic survey data. Accuracy and precision of estimates, however, depend on the number of replicate surveys, and on adjustments made for animals unavailable to (availability bias)
Véronique Lesage, Sara Wing, Alain F. Zuur, Jean-François Gosselin, M. Tim Tinker, Arnaud Mosnier, Anne P. St-Pierre, Robert Michaud, Dominique Berteaux   +8 more
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source