Results 81 to 90 of about 464,371 (256)

Lithium abundances in CEMP stars

, 2012
Carbon-enhanced metal-poor (CEMP) stars are believed to show the chemical imprints of more massive stars (M > 0.8 Msun) that are now extinct. In particular, it is expected that the observed abundance of Li should deviate in these stars from the standard ...
Abia, Alvarez, Amanda Karakas, Aoki, Aoki, Aoki, Aoki, Aoki, Aoki, Aoki, Asplund, Asplund, Bertrand Plez, Christlieb, Cohen, Cristallo, Denissenkov, Denissenkov, Eggleton, Frebel, Goriely, Herwig, Hobbs, Iwamoto, Jennifer A. Johnson, Johnson, Johnson, Karakas, Lawler, Lucatello, Lucatello, Lucatello, Lucatello, Lucatello, Masseron, Nollett, Norbert Christlieb, Norris, Norris, Norris, Norris, Palmerini, Preston, Richard, Roederer, Ryan, Ryan, Sara Lucatello, Siess, Sneden, Spite, Spite, Steffen, Suda, Suda, Thomas Masseron, Thompson, Thorburn, Timothy C. Beers, Tsangarides, VandenBerg   +60 more
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Zinc abundances of planetary nebulae

, 2014
Zinc is a useful surrogate element for measuring Fe/H as, unlike iron, it is not depleted in the gas phase media. Zn/H and O/Zn ratios have been derived using the [Zn IV] emission line at 3.625um for a sample of nine Galactic planetary nebulae, seven of ...
Dinerstein, Harriet L., Smith, Christina L., Zijlstra, Albert A.   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Direct determination of the astrophysical reaction rate of 141Pr(γ, n)140Pr at the SSRF-SLEGS

Astronomy & Astrophysics
Context. The 141Pr(γ, n) cross-section is critical to the nucleosynthesis of p-nuclides 136,138Ce in thermonuclear supernovae and in massive stars. The photonuclear reaction of 141Pr(γ, n) provides a new method for producing 140Pr radioisotopes for ...
Hu J. H., An Z. D., Hao Z. R., Li Z. C., Fan G. T., Wang H. W., Ma Y. G., Liu T., Liang H., Wen H. H., Guo C. C.   +10 more
doaj   +1 more source

Stellar Populations of the Galactic Disk: Metallicity Distribution and Kinematics

Open Astronomy, 2003
Metallicities and distances have been determined from Vilnius photometry for an in situ sample of nearly 650 stars in eight proper-motion fields at high Galactic latitudes.
Bartašiūtė S., Aslan Z., Boyle R. P., Kharchenko N. V., Ossipkov L. P., Sperauskas J.   +5 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Impact of in situ nuclear networks and atomic opacities on neutron star merger ejecta dynamics, nucleosynthesis, and kilonovae

Astronomy & Astrophysics
Context. Binary neutron star merger (BNSM) ejecta are key sites of rapid neutron capture (r-process) nucleosynthesis and they produce kilonovae powered by the radioactive decay of freshly synthesized nuclei.
Magistrelli Fabio, Bernuzzi Sebastiano, Perego Albino, Jacobi Maximilian, Fontes Christopher J.   +4 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Violent mergers revisited: The origin of the fastest stars in the Galaxy

Astronomy & Astrophysics
Binary systems of two carbon-oxygen white dwarfs are one of the most promising candidates for the progenitor systems of Type Ia supernovae. Violent mergers, where the primary white dwarf ignites when the secondary white dwarf smashes into it while being ...
Pakmor Rüdiger, Shen Ken J., Bhat Aakash, Rajamuthukumar Abinaya Swaruba, Collins Christine E., O’Donnell Cillian, Bauer Evan B., Callan Fionntan P., Röpke Friedrich K., Pollin Joshua M., Maguire Kate, Kwok Lindsey A., Seth Ravi, Taubenberger Stefan, Justham Stephen   +14 more
doaj   +1 more source