Results 81 to 90 of about 627,744 (337)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Direct determination of the astrophysical reaction rate of 141Pr(γ, n)140Pr at the SSRF-SLEGS

open access: yesAstronomy & Astrophysics
Context. The 141Pr(γ, n) cross-section is critical to the nucleosynthesis of p-nuclides 136,138Ce in thermonuclear supernovae and in massive stars. The photonuclear reaction of 141Pr(γ, n) provides a new method for producing 140Pr radioisotopes for ...
Hu J. H.   +10 more
doaj   +1 more source

Abundances in bulge stars from high-resolution, near-IR spectra I. The CNO elements observed during the science verification of CRIRES at VLT

open access: yes, 2009
The formation and evolution of the Milky Way bulge is not yet well understood and its classification is ambiguous. Constraints can, however, be obtained by studying the abundances of key elements in bulge stars.
A. Smette   +47 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Impact of in situ nuclear networks and atomic opacities on neutron star merger ejecta dynamics, nucleosynthesis, and kilonovae

open access: yesAstronomy & Astrophysics
Context. Binary neutron star merger (BNSM) ejecta are key sites of rapid neutron capture (r-process) nucleosynthesis and they produce kilonovae powered by the radioactive decay of freshly synthesized nuclei.
Magistrelli Fabio   +4 more
doaj   +1 more source

Stellar Populations of the Galactic Disk: Metallicity Distribution and Kinematics

open access: yesOpen Astronomy, 2003
Metallicities and distances have been determined from Vilnius photometry for an in situ sample of nearly 650 stars in eight proper-motion fields at high Galactic latitudes.
Bartašiūtė S.   +5 more
doaj   +1 more source

Chemical composition of A and F dwarfs members of the Pleiades open cluster

open access: yes, 2008
Abundances of 18 chemical elements have been derived for 16 A (normal and chemically peculiar CP) and 5 F dwarfs members of the Pleiades open cluster in order to set constraints on evolutionary models.
Abt   +37 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Violent mergers revisited: The origin of the fastest stars in the Galaxy

open access: yesAstronomy & Astrophysics
Binary systems of two carbon-oxygen white dwarfs are one of the most promising candidates for the progenitor systems of Type Ia supernovae. Violent mergers, where the primary white dwarf ignites when the secondary white dwarf smashes into it while being ...
Pakmor Rüdiger   +14 more
doaj   +1 more source

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