Results 81 to 90 of about 627,744 (337)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Direct determination of the astrophysical reaction rate of 141Pr(γ, n)140Pr at the SSRF-SLEGS
Context. The 141Pr(γ, n) cross-section is critical to the nucleosynthesis of p-nuclides 136,138Ce in thermonuclear supernovae and in massive stars. The photonuclear reaction of 141Pr(γ, n) provides a new method for producing 140Pr radioisotopes for ...
Hu J. H. +10 more
doaj +1 more source
The formation and evolution of the Milky Way bulge is not yet well understood and its classification is ambiguous. Constraints can, however, be obtained by studying the abundances of key elements in bulge stars.
A. Smette +47 more
core +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Context. Binary neutron star merger (BNSM) ejecta are key sites of rapid neutron capture (r-process) nucleosynthesis and they produce kilonovae powered by the radioactive decay of freshly synthesized nuclei.
Magistrelli Fabio +4 more
doaj +1 more source
Stellar Populations of the Galactic Disk: Metallicity Distribution and Kinematics
Metallicities and distances have been determined from Vilnius photometry for an in situ sample of nearly 650 stars in eight proper-motion fields at high Galactic latitudes.
Bartašiūtė S. +5 more
doaj +1 more source
Chemical composition of A and F dwarfs members of the Pleiades open cluster
Abundances of 18 chemical elements have been derived for 16 A (normal and chemically peculiar CP) and 5 F dwarfs members of the Pleiades open cluster in order to set constraints on evolutionary models.
Abt +37 more
core +3 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Violent mergers revisited: The origin of the fastest stars in the Galaxy
Binary systems of two carbon-oxygen white dwarfs are one of the most promising candidates for the progenitor systems of Type Ia supernovae. Violent mergers, where the primary white dwarf ignites when the secondary white dwarf smashes into it while being ...
Pakmor Rüdiger +14 more
doaj +1 more source

