Results 141 to 150 of about 1,169,779 (313)

Warm family of origin is associated with earlier disclosure of sexual abuse. [PDF]

Eur J Psychotraumatol
Barge C, Sijbrandij M, Both S, van Ditzhuijzen J, Bicanic I.   +4 more
europepmc   +1 more source

Relationship between Opium Abuse and Severity of Depression in Type 2 Diabetic Patients

, 2012
Zahra Sepehrmanesh, Hossein Sarmast, Ali Kord Valeshabad   +2 more
openalex   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li, Xiaochen Zhang, Jiangwei Xia, Shuang Liu, Yushan Du, Sihan Li, Shukui Zhang, Yong Zhang, Fen Ji, Jianwei Jiao, Jingjing Zhang   +10 more
wiley   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Abuse of people with mental illnesses perpetrated by healthcare professionals: a scoping review. [PDF]

BMJ Open
Matoba K, Teshima T, Yayama S, Koto Y, Miki A.   +4 more
europepmc   +1 more source

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

Advanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang, Shaoju Jin, Shaoying Wen, Wen Zeng, Chen Wang, Jingyu Wang, Qingyun Song, Guizhong Li, Pengzhi Yin, Yuhui Liao, Yuee Chai, Huiping Zhang, Shengchao Ma   +12 more
wiley   +1 more source

Bidirectional Associations Between Substance Abuse and Psoriasis: A Prospective Cohort Study. [PDF]

Psoriasis (Auckl)
Che X, Zhou J, Wang A, Guo J, Zhang C, Xiao Y.   +5 more
europepmc   +1 more source

DEA Briefs & Background, Drugs and Drug Abuse, State Factsheets, Nebraska

, 2004
US Department of Justice; Drug Enforcement Administration
openalex   +1 more source

Parameters of reported childhood sexual abuse and assault in adolescents and adults with borderline personality disorder [PDF]

, 2020
Christina M. Temes, Laura R. Magni, Blaise Aguirre, Marianne Goodman, Maria Elena Ridolfi, Mary C. Zanarini   +5 more
openalex   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source