Results 31 to 40 of about 535,088 (168)

Characteristics and Correlates of Psychiatric Problems in Wives of Men with Substance-related Disorders, Kermanshah, Iran

open access: yesOman Medical Journal, 2018
Objectives: We sought to evaluate the characteristics and correlates of psychiatric problems in the wives of men with substance-related disorders. Methods: Four-hundred and fifty women whose husbands had substance-related disorders were selected by ...
Toraj Ahmadi Juibari   +6 more
doaj   +1 more source

Responsiveness to change in health status of the EQ-5D in patients treated for depression and anxiety

open access: yesHealth and Quality of Life Outcomes, 2023
Background The EQ-5D is a commonly used generic measure of health but evidence on its responsiveness to change in mental health is limited. This study aimed to explore the responsiveness of the five-level version of the instrument, the EQ-5D-5 L, in ...
Kenneth Sandin   +6 more
doaj   +1 more source

Robust brain hyperglycemia during general anesthesia: relationships with metabolic brain inhibition and vasodilation

open access: yesFrontiers in Physiology, 2016
Glucose is the main energetic substrate for the metabolic activity of brain cells and its proper delivery into the extracellular space is essential for maintaining normal neural functions.
R. Aaron eBola, Eugene A Kiyatkin
doaj   +1 more source

Whole brain dynamics during optogenetic self-stimulation of the medial prefrontal cortex in mice

open access: yesCommunications Biology, 2021
Cover et al. develop a method that permits functional MRI of brain dynamics while mice are cued to perform an operant task: licking a spout to receive optogenetic stimulation to the medial prefrontal cortex.
Christopher G. Cover   +6 more
doaj   +1 more source

Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation

open access: yesJournal of Neuroinflammation, 2023
Background Neuroinflammation is a widely studied phenomenon underlying various neurodegenerative diseases. Earlier study demonstrated that pharmacological activation of GPR110 in both central and peripheral immune cells cooperatively ameliorates ...
Sharmistha Banerjee   +3 more
doaj   +1 more source

Methylphenidate reorganizes cortical hierarchy through dopaminergic modulation

open access: yesNature Communications
Dopaminergic signaling shapes large-scale brain network architecture, constraining neural communication along a principal gradient that spans unimodal sensorimotor to transmodal association cortices.
Dardo Tomasi   +12 more
doaj   +1 more source

TMS via temporal summation: high-frequency rTMS at subthreshold intensity induces suprathreshold motor response in rats

open access: yesBrain Stimulation, 2023
Hieu Nguyen   +4 more
doaj   +1 more source

Deviation in development of dorsal association tracts during preadolescence links to concurrent and future cognitive performance and transdiagnostic psychopathology

open access: yesNature Communications
Many psychiatric disorders begin during adolescence, coinciding with the rapid development of brain white matter (WM). However, it remains unclear whether deviations from normal WM development during this period contribute to psychopathology.
Danni Wang   +13 more
doaj   +1 more source

Correspondence between cerebral glucose metabolism and BOLD reveals relative power and cost in human brain

open access: yesNature Communications, 2019
The brain primarily uses glucose to generate energy, but the relationship of neuronal activity to glucose utilization is not necessarily a simple linear one.
Ehsan Shokri-Kojori   +5 more
doaj   +1 more source

The effectiveness of different singly administered high doses of buprenorphine in reducing suicidal ideation in acutely depressed people with co-morbid opiate dependence: a randomized, double-blind, clinical trial

open access: yesTrials, 2018
Background Buprenorphine is usually administered to treat opioid use disorder and pain syndromes. This research presents the first study regarding the effectiveness of different singly administered high doses of buprenorphine (a partial opioid agonist ...
Jamshid Ahmadi   +2 more
doaj   +1 more source

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