Results 31 to 40 of about 15,981 (257)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

EU Competition Law Policy versus Intellectual Property Rights: A Study of the Microsoft Case

open access: yesCroatian Yearbook of European Law and Policy, 2010
The constant tension between intellectual property rights and competition policy has recently culminated in the Microsoft case. This article examines the tests applied by the European Commission and CFI in finding Microsoft’s behaviour tantamount to the ...
Irena Tušek
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

THE ABUSE OF DOMINANT POSITION - RESTRICTING COMPETITION PRACTICE. CASE STUDY: ENI [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2013
The abuse of dominant position along with cartel, merger and state aid are practices restricting competition strictly regulated at EU level. These practices can have a disastrous effect on the internal market harming both competition especially consumers.
BERINDE Mihai, FORA Andreea-Florina
doaj  

Individual Abuse of Collective Dominance in Cellular Communications: Problems of Identification

open access: yesСовременная конкуренция, 2021
Recently, discussions about the validity of the Russian practice of establishing the facts of individual abuse of collective dominance have been escalating: many experts point to a contradiction between the meaning of collective dominance, in which a ...
Andrey E. Shastitko   +2 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Abuse of Dominant Position by Platforms through Data: International Experience

open access: yesСовременная конкуренция
The article explores data as a key source of market power for digital platforms and as an independent object of antitrust analysis. It also examines the role of data as a factor in shaping the dominant position of digital platforms and their use in anti ...
Maria G. Girich, Antonina D. Levashenko
doaj   +1 more source

Digital Economy, Big Data and Competition Law

open access: yesMarket and Competition Law Review, 2019
Big data has a very important role in the digital economy, because firms have accurate tools to collect, store, analyse, treat, monetise and disseminate voluminous amounts of data.
Roberto Augusto Castellanos Pfeiffer
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Protection of Competition from Abuse with Dominant Positions and Anticompetitive Agreements in the Kosovo Market

open access: yesStudia Iuridica Lublinensia, 2022
Protection of competition from abuse with dominant positions and anticompetitive agreements in the Kosovo market is governed by the Constitution of Kosovo and the Kosovo Law on Protection of Competition.
Valbon Mulaj
doaj   +1 more source

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