Results 61 to 70 of about 2,262,511 (306)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

A Comprehensive Loss Model and Comparison of AC and DC Boost Converters

open access: yesEnergies, 2021
DC microgrids have become a prevalent topic in research in part due to the expected superior efficiency of DC/DC converters compared to their AC/DC counterparts.
Daniel L. Gerber   +6 more
doaj   +1 more source

Surface Influence on Flux Penetration into HTS Bulks

open access: yes, 1999
The influence of surface treatment on AC loss in melt-processed quasi-single crystal HTS was investigated with resonance oscillations technique. We have found that amplitude dependencies of AC loss on magnetic field amplitude become rather complicated ...
Kordyuk, A. A.   +3 more
core   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers. [PDF]

open access: yesPLoS ONE, 2014
HIV replication is only partially controlled by HIV-specific activated effector T cells in chronic HIV infection and strategies are warranted to improve their efficacy.
Andreas Lind   +5 more
doaj   +1 more source

Investigation of AC Loss in HTS Cross-Conductor Cables for Electrical Power Transmission

open access: yes, 2018
This paper presents the alternating current (AC) loss analysis on high-temperature superconductor (HTS) Cross-Conductor (CroCo) cables, in order to evaluate whether they could be utilized for electrical power transmission.
Coombs, T. A.   +2 more
core   +1 more source

Influence of PWM on the proximity loss in permanent magnet brushless AC machines [PDF]

open access: yes, 2008
The winding copper loss can be significantly increased due to skin and proximity eddy current effects. The skin and proximity losses due to fundamental frequency current has been investigated in literature, but the influence of PWM on the skin and ...
Bremner, J.   +5 more
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

A distinct method to eliminate the induced voltage in AC loss determination without phase control

open access: yesAIP Advances, 2020
AC loss is often considered one of the most important design parameters that guide the fabrication of superconducting devices. Thus, the electrometric method to determine AC loss of superconductors is crucial.
Liuyang Shen   +3 more
doaj   +1 more source

Influence of the voltage taps position on the self-field DC and AC transport characterization of HTS superconducting tapes

open access: yes, 2013
The current-voltage (I-V) curve is the basic characteristic of a superconducting wire or tape. Measuring I-V curves is generally problematic when samples have poor stabilization.
Goldacker, W.   +4 more
core   +1 more source

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