Results 31 to 40 of about 150 (145)

High‐Resolution Characterization of Protein‐Conjugated, mRNA‐Loaded Lipid Nanoparticles by Analytical Ultracentrifugation

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles containing messenger RNA are characterized by sedimentation velocity analytical ultracentrifugation using UltraScan's new Custom Grid algorithm to provide multi‐dimensional distributions for partial specific volume (particle density), molar mass, sedimentation, diffusion, and hydrodynamic radius.
Sophia Bird   +8 more
wiley   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni   +11 more
wiley   +1 more source

A produção científica publicada pelo Instituto Oswaldo Cruz no período 1900 a 1917: um estudo exploratório Instituto Oswaldo Cruz scientific publication from 1900 to 1917, an exploratory study

open access: yesHistória, Ciências, Saúde: Manguinhos, 2002
O presente trabalho é um estudo exploratório sobre a produção científica publicada pelo Instituto Oswaldo Cruz (IOC) no período 1900-17. Busca-se caracterizar a produção inicial do instituto e o desempenho de seus cientistas no aspecto informacional ...
Wanda Latmann Weltman
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee   +7 more
wiley   +1 more source

A gestão de recursos humanos em uma instituição pública brasileira de ciência e tecnologia em saúde: o caso Fiocruz The management of human resources in a public institution of science and technology in health: the Fiocruz case

open access: yesRevista de Administração Pública, 2010
A partir da década de 1970, a crise do padrão de acumulação capitalista firmado no binômio taylorismo-fordismo levou à sua substituição por formas produtivas flexibilizadas e desregulamentadas.
Márcio Luiz Braga Corrêa de Mello   +1 more
doaj   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman   +12 more
wiley   +1 more source

Spiro‐Phenothiazine Hole‐Transporting Materials: Unlocking Stability and Scalability in Perovskite Solar Cells

open access: yesAdvanced Materials, EarlyView.
Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora   +17 more
wiley   +1 more source

Spin‐Crossover Confinement in Mesoporous Matrices Enables Tunable Porosity for Molecular Sensing

open access: yesAdvanced Materials Interfaces, EarlyView.
The integration of hierarchically organized porous frameworks with spin‐crossover nanodomains enables cooperative interactions across multiple length scales. This hybrid design merges dynamic molecular switching with tunable porosity, yielding materials whose structural and functional responses are actively modulated by confinement and guest uptake ...
Lucia B. Pizarro   +3 more
wiley   +1 more source

La formación ambiental desde la integración posgrado-investigación en la Universidad de Pinar del Río

open access: yesRevista de Ciencias Médicas de Pinar del Río, 2018
Introducción: la Universidad como institución social encargada de la formación de profesionales, tiene ante sí el reto de ejercer una actitud de liderazgo en la construcción de alternativas que incidan en la prevención, mitigación y/o solución de los ...
Dora Lilia Márquez Delgado   +3 more
doaj  

Genetic Diagnosis and Discovery Enabled by Large Language Models

open access: yesAdvanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu   +25 more
wiley   +1 more source

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