Results 51 to 60 of about 2,063 (279)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Ableism in academia: theorising disabilities and chronic illnesess in higher education

, 2020
Rather than embracing difference as a reflection of wider society, academic ecosystems seek to normalise and homogenise ways of working and of being a scholar – as a consequence, ableism in academia is endemic.

core  

Data_Sheet_2_Infusing disability equity within rehabilitation education and practice: A qualitative study of lived experiences of ableism, allyship, and healthcare partnership.PDF

, 2022
BackgroundAddressing issues of diversity, equity, and inclusion (DEI) has become central in implementing inclusive and socially responsible rehabilitation education and clinical practice. Yet, the constructs of disability and d/Deaf identity and culture,
Danbi Lee (3682918), Lesley M. Ellis (13186650), Heather A. Feldner (7974245), Mark K. Harniss (13186653), Heather D. Evans (13186644), Katherine Chamblin (13186647), Joanne Woiak (13186656)   +6 more
core   +1 more source

Ability expectations in collaborative research: Ethical reflections from three empirical studies with disability communities

Research Ethics Review
This study critically explores ability expectations in collaborative research with disability communities to highlight ethical consequences and outline an ableism-critical research practice.
Rahel More
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Data_Sheet_1_Infusing disability equity within rehabilitation education and practice: A qualitative study of lived experiences of ableism, allyship, and healthcare partnership.PDF

, 2022
BackgroundAddressing issues of diversity, equity, and inclusion (DEI) has become central in implementing inclusive and socially responsible rehabilitation education and clinical practice. Yet, the constructs of disability and d/Deaf identity and culture,
Danbi Lee (3682918), Lesley M. Ellis (13186650), Heather A. Feldner (7974245), Mark K. Harniss (13186653), Heather D. Evans (13186644), Katherine Chamblin (13186647), Joanne Woiak (13186656)   +6 more
core   +1 more source

From supercrip to techno supercrip

Current Issues in Sport Science
Participation in sport on all levels, physical activity, leisure and recreation is seen as important for disabled people but at the same time barriers are reported for disabled people.
Gregor Wolbring
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Crip Flexibility and Painful Analysis: Critical Disability Methodologies of Swedish Welfare State Austerity

Scandinavian Journal of Disability Research
This article contributes to methodological debates in critical disability studies (CDS) by introducing the concepts of crip flexibility and painful analysis to describe how disability research is shaped under austerity.
Christine Bylund
doaj   +1 more source

“Te Kore and the Artiste within: De-Tyrannizing Autistic Viewpoints in Life, Self, and Identity through Creative Methodologies”

International Journal of Qualitative Methods, 2023
The voices of the autistic community have been systematically forfeited in research and practice, both as a consequence of the double empathy problem and, as a direct result of albeist methodic approaches to researching and representing autism (Milton ...
Michelle Whitehead
doaj   +1 more source