Results 41 to 50 of about 6,736,675 (246)
, 2023 This is a painting of a Disabled person pointing their cane at the sky while lightning shoots out of it. It is representative of the resilience of the Disability community in our fight to dismantle ableism.
Khan, Eman
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Visibility of Disability: Ableism in Indian Film, Politics and Sports [PDF]
, 2023 “Visibility of Disability: Ableism in Indian Film, Politics and Sports” is a study of the representation of the disabled in Indian film, politics, and sports, where the representation of anything matters the most since these three are the major cultural ...
Stenza Augustine, Abhaydev C.S
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
YouthAdverse childhood experiences (ACEs) are negative but preventable experiences within family and social environments. Originally focused on abuse and household dysfunction, ACE indicators now include many social factors, such as social determinants of ...
Gregor Wolbring, Parneet Dhindsa
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Academic Ableism and Its Alternatives
, 2022 In this interactive talk, we will collaborate to address the ableist attitudes, policies, and practices that are built into higher education. We will also interrogate the minimal and temporary means we have been given to address inequities, and the cost ...
Dolmage, Jay
core
Research Ethics ReviewThis study critically explores ability expectations in collaborative research with disability communities to highlight ethical consequences and outline an ableism-critical research practice.
Rahel More
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source