Results 31 to 40 of about 228,273 (260)

Student Perceptions of Academic Functioning During the COVID-19 Pandemic in Germany

COVID
Background: The COVID-19 pandemic posed unprecedented challenges to higher education in Germany, necessitating a rapid transition to remote learning. This study evaluates the impact of the pandemic on academic functioning among German university students.
Pauline A. Hendriksen, Anna H. Koyun, Johan Garssen, Ann-Kathrin Stock, Joris C. Verster   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Collaborative learning in small groups in an online course – a case study

BMC Medical Education, 2022
Background The ability to learn collaboratively and work in teams is an essential competency in both educational and healthcare settings, and collaborative student activities are acknowledged as being an important part of the pedagogical approach in ...
Mildrid Jorunn Haugland, Ivar Rosenberg, Katrine Aasekjær   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

ADHD in higher education institutions in Ireland- services, supports and student needs

Cogent Education
It is estimated that up to 40,000 students in Higher Education Institutions (HEIs) in Ireland have Attention-Deficit/Hyperactivity Disorder (ADHD). The aim of this study is to determine the existing ADHD services and supports in HEIs in Ireland and to ...
Christine Boyd, Margo Wrigley, Ken Kilbride, Aisling Mulligan, Jessica Bramham   +4 more
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

The functioning of academic employees in a dynamic South African higher education environment

Frontiers in Education, 2023
IntroductionThe higher education sector is experiencing changes in the profile of employees and stakeholders. Current employees are expected to function effectively and efficiently in institutions to achieve individual and organisational goals.
Thapelo D. ChaaCha, Thapelo D. ChaaCha, Elrie Oosthuysen, Elrie Oosthuysen   +3 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

COVID-19 Lockdown Effects on Sleep, Immune Fitness, Mood, Quality of Life, and Academic Functioning: Survey Data from Turkish University Students

Data
Previous studies from the Netherlands, Germany, and Argentina revealed that the 2019 coronavirus disease (COVID-19) pandemic and associated lockdown periods had a significant negative impact on the wellbeing and quality of life of students.
Pauline A. Hendriksen, Sema Tan, Evi C. van Oostrom, Agnese Merlo, Hilal Bardakçi, Nilay Aksoy, Johan Garssen, Gillian Bruce, Joris C. Verster   +8 more
doaj   +1 more source