Results 31 to 40 of about 1,567,947 (289)

Whalesong [PDF]

open access: yes, 1986
UAJ analyzed by committee -- Roundtable talks to be held -- USUAJ members attend meeting -- USUAJ election results tallied -- UAJ: under close scrutiny -- Smith speaks out -- LETTERS -- Macbeth--"intriguing, enjoyable" -- Queen releases hot new album ...

core  

Institutionalising future geographies of financial inclusion: national legitimacy versus local autonomy in the British credit union movement. [PDF]

open access: yes, 2002
This paper provides a critical overview of recent developments in British credit union development, and contributed to the broader analysis of alternative financial/economic spaces and (the geographies of) alterity.
Fuller, Duncan, Jonas, Andrew
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Academic news, awards, congresses, workshops

open access: yesSouth African Journal of Radiology, 2008
No abstract available.
Savvas Andronikou
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

The Relationship Listening Intensively Toward Ability to Write News Content by Student Eighth Grade of SMP Negeri 1 Atap Tampahan in Academic Year 2017/2018 [PDF]

open access: yes, 2018
This study aims to determine The Relationship Listening Intensively Toward Ability to Write News Content by Student Eighth Grade of SMP Negeri 1 Atap Tampahan in Academic Year 2017/2018.The Population of this Study were the Student Eighth Grade of SMP ...
Saragih, M. (Mariatih)   +1 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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