Results 51 to 60 of about 2,307,578 (311)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

The Effect of Personality characteristics and Perceived Social Support on Gratitude with the Mediation of Academic Stress and Self efficacy [PDF]

پژوهشنامه روانشناسی مثبت, 2019
The purpose of this study was to determine the relationship between personality traits and perceived social support with gratitude through educational mediation and academic self-efficacy.
seyed mehdi poorseyed, Farhad Khormaei
doaj   +1 more source

GAMBARAN ACADEMIC STRESS PADA MAHASISWA PECINTA ALAM [PDF]

, 2023
Suicide cases now occur frequently, and most of these cases have an impact on students. Where students who are in their transition period will have a high incidence of suicide due to academic pressure and also the new responsibilities they feel when ...
Bahar, Sitii Magfirah Bahar
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Coping with Thesis Writing: An Analysis of Stress Management Techniques in Higher Education

Jurnal Bimbingan dan Konseling Terapan
This research explores the relationship between Problem-Focused Coping and Academic Stress among students at Satya Wacana Christian University. In an academic environment where students face immense pressure, particularly during the thesis-writing phase,
Alvina Della Ardiana, Christiana Hari Soetjiningsih   +1 more
doaj   +1 more source

Pengaruh Konseling Kelompok terhadap Pengurangan Stres Akademik Siswa Kelas X Sman 2 Siakhulu T.p 2014/2015 [PDF]

, 2015
The title of this research is ‘' Effect of Group Counseling towards the Reduction of Academic Stress of First – Year Students of Academic Year 2014/2015 at SMAN 2 Siak Hulu''.
Arlizon, R. A. (Raja), Dena, P. R. (Putri), Umari, T. U. (Tri)   +2 more
core  

Chinese students' psychological and sociocultural adjustments to Britain: an empirical study [PDF]

, 2006
This paper reports an empirical study of the psychological and sociocultural adjustments of two cohorts of Chinese students taking a foundation course in English language at a British university.
Spencer-Oatey, Helen, Xiong, Zhaoning
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

How Has the COVID-19 Crisis Affected the Academic Stress of University Students? The Role of Teachers and Students

Frontiers in Psychology, 2021
The effects of the COVID-19 pandemic have required substantial adjustments in terms of university teaching–learning processes. The aim of this study was to verify whether there were significant differences between the academic year of 2020 and the two ...
Jesús de la Fuente, Jesús de la Fuente, Mónica Pachón-Basallo, Flavia H. Santos, Francisco J. Peralta-Sánchez, María Carmen González-Torres, Raquel Artuch-Garde, Paola V. Paoloni, Martha L. Gaetha   +8 more
doaj   +1 more source