Results 31 to 40 of about 8,732,479 (262)

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Recursive Queried Frequent Patterns Algorithm: Determining Frequent Pattern Sets from Database

open access: yesInformation
Frequent pattern mining is a fundamental method for Data Mining, applicable in market basket analysis, recommendation systems, and academic analytics. Widely adopted and foundational algorithms such as Apriori and FP-Growth, which represent the standard ...
Ishtiyaq Ahmad Khan   +3 more
doaj   +1 more source

Exploring the challenges and efforts implemented to improve the academic performance and success of nursing students at a university in the Western Cape

open access: yesInternational Journal of Africa Nursing Sciences, 2020
Satisfactory academic performance and success of undergraduate nursing students is a fundamental goal for schools of nursing worldwide. However, many students are confronted with various challenges that may hinder this endeavour.
Katlego Dumisani Trevor Mthimunye   +1 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Method of images and influence of lighting radiation intensity on student learning effectivity in hygiene and ergonomics of education

open access: yesAnnals of Mechnikov's Institute, 2019
42 years ago, studying digital-light-color analogies in combination of mechanoreceptors, we created Method of teaching any subject, based on Images and Patterns.
B Farber, D Manzini
doaj  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Defining student success as a multidimensional concept: A scoping review

open access: yesInternational Journal of Educational Research Open
Student success is a critically important concept in educational assessment and research, yet a comprehensive synthesis of its defining elements remains absent.
Jorien Vugteveen   +2 more
doaj   +1 more source

Allantoin: A Potential Compound for the Mitigation of Adverse Effects of Abiotic Stresses in Plants

open access: yesPlants, 2023
Stress-induced alterations vary with the species of plants, the intensity and duration of the exposure, and stressors availability in nature or soil. Purine catabolism acts as an inherent defensive mechanism against various abiotic stresses and plays a ...
Rasleen Kaur   +3 more
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

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