Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The writer-reader relationship in academic writing [PDF]
In the past, we were taught to think that writing and reading were two separate skills and the writer was more important than the reader because he or she was seen as an active composer of messages while the reader was seen only as a passive receiver of ...
Kamal, Banu
core
Reaching In, Reaching Out: A Tale of Administrative Experimentation and the Process of Administrative Inclusion [PDF]
Universities often have a variety of academic programs and initiatives dedicated to the goal of helping students achieve effective communication skills, but these programs and initiatives can change quickly during different moments of institutional and ...
PreJean, Kelli
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Challenges and potentials for writing centres in South African tertiary institutions [PDF]
This is an Accepted Manuscript of an article published by Taylor & Francis in South African Journal of Higher Education in 2010, available online: http://reference.sabinet.co.za/webx/access/electronic_journals/high/high_v24_n4_a2.pdf.There are many ...
Archer, Arlene
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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Writing the different academic papers such as essays and articles at the university requires from students to follow certain conventions proper to formal and cautious academic writing.
Nassima Mechitoua
doaj
Approaches Reflected in Academic Writing MOOCs
Since it was first introduced in 2008, Massive Open Online Courses (MOOCs) have been attracting a lot of interest. Since then, MOOCs have emerged as powerful platforms for teaching and learning academic writing.
Subeom Kwak
doaj +1 more source
A methodology for enhancing student writing in the discipline through complementary and collaborative working between central and school based writing development provision [PDF]
Academic literacies theory argues that academic writing is currently caught up in unequal power relationships which 'problematize the student' (Lea and Street 1998) and thus argues for a change in focus from a 'skills' model to the adoption of a more ...
Johnson, S, Trafford, S
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