Results 71 to 80 of about 55,832 (307)

Science advice to governments: diverse systems, common challenges [PDF]

open access: yes, 2014
This briefing paper formed the basis of discussions at the 'Science Advice to Governments' summit, which took place in Auckland, New Zealand from 28-29 August 2014, and was attended by science advisors and policymakers from 48 ...
Allen, Kristiann   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The U.S. Commitment to Global Health: Recommendations for the New Administration [PDF]

open access: yes, 2008
Outlines the need for making a commitment to improving global health an integral part of U.S. foreign policy. Suggestions include creating a White House Interagency Committee on Global Health and directing more funds to chronic disease ...

core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Performance Analysis of Human Resources Higher Education in Kopertis III Jakarta

open access: yesJurnal Pendidikan Ekonomi dan Bisnis (JPEB), 2018
This study was to find out and understand the profile of Higher Education (PT) Human Resources, the quality of Human Resources for Higher Education, and determine the quality of Higher Education in Kopertis III Jakarta, by using data from 2015 to 2017 ...
Prasetio Ariwibowo, Tjipto Djuhartono
doaj   +1 more source

Patterns of preservation, restructuring and survival: science and technology policy in Russia in the post Soviet era [PDF]

open access: yes, 2002
This paper analyses the role of S&T policy in the adjustment and restructuring of the Russian S&T system in the post-Soviet period. The principal argument is that the adjustment of the S&T system in Russia has been evolving between the 'preservation of S&
Radošević, S.
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Evolution of “Academic Sector” of Soviet Historical Science in 1920s—1960s.

open access: yesНаучный диалог, 2020
The evolution of the “academic sector” of Soviet historical science is analyzed, the process of its formation and subsequent development is considered. The relevance of the study is due to the methodological searches of modern historiography, focused on ...
O. V. Metel
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Integrating Emerging Areas of Nursing Science into PhD Programs [PDF]

open access: yes, 2015
The Council for the Advancement of Nursing Science aims to “facilitate and recognize life-long nursing science career development” as an important part of its mission.
Conley, Yvette P.   +10 more
core   +1 more source

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