Results 1 to 10 of about 3,619 (165)
A new method for the preparation of pure acamprosate calcium with a micron particle size [PDF]
Journal of Particle Science and Technology, 2022 Considering that preparing microparticle drugs enhances their solubility and bioactivity, it is the pharmaceutics’ interest to have more information about the drug’s particle size; hence, it is essential to study a drug’s particle size and morphology. So
Fatemeh Mobayyen Jarihani +1 more
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Acamprosate reduces ethanol intake in the rat by a combined action of different drug components
Scientific Reports, 2023 Alcohol misuse accounts for a sizeable proportion of the global burden of disease, and Campral® (acamprosate; calcium-bis-(N-acetylhomotaurinate)) is widely used as relapse prevention therapy.
Karin Ademar +6 more
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Frontiers in Pharmacology, 2022 Acamprosate is an anti-craving drug used in alcohol use disorder (AUD) pharmacotherapy. However, only a subset of patients achieves optimal treatment outcomes. The identification of predictive biomarkers of acamprosate treatment response in patients with
Ming-Fen Ho +14 more
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Veteran adherence to oral versus injectable AUD medication treatment [PDF]
Mental Health Clinician, 2021 Introduction: AUD medication treatment has been shown to improve outcomes compared with placebo when confined to per-protocol analysis. The same outcomes, however, have not always been maintained in intent-to-treat analysis, thus suggesting adherence may
Hayden Stewart, PharmD +3 more
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Investigation of the Effect of Acamprosate Treatment on Heart Contractions in Alcohol-Dependent Rats
Genel Tıp Dergisi, 2022 Background/ Aim: Chronic alcohol use leads to impaired heart contraction and also causes a direct toxic effect on myocardial function. Acamprosate, which is widely used in alcohol dependence, is not known to have a pharmacological effect on cardiac ...
Aysu Şen +2 more
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Deterrent Action of Acamprosate: A Case Report [PDF]
Addiction and Health, 2019 Background: Among the three pharmacological agents available for alcohol de-addiction, acamprosate and naltrexone are considered anti-craving agents. Among these two, acamprosate is better tolerated, has low abuse potential, and is safe in overdose.
MAMIDIPALLI SAI SPOORTHY +2 more
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Pharmaceutics, 2020 Acamprosate is an anionic drug substance widely used in treating symptoms of alcohol withdrawal. It was recently shown that oral acamprosate absorption is likely due to paracellular transport.
Irina E. Antonescu +8 more
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Efficacy of acamprosate in the treatment of alcohol-dependent outpatients [PDF]
Brazilian Journal of Psychiatry, 2003 OBJECTIVE: To evaluate the efficacy and security of acamprosate in the treatment of 75 men, aged 18 to 59 years, with diagnosis of alcohol dependence according to the ICD-10. METHODS: Double-blind, placebo-controlled study, 24-week long. After a one-week
Danilo Antonio Baltieri +1 more
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Hypersalivation and coarse tremors as uncommon side effects of acamprosate: A case report
European Psychiatry, 2021 Introduction Mr. X, a 39-year-old man presented to us with a history of alcohol use from the last 12-15 years in a dependence pattern with tolerance, uncomplicated withdrawal symptoms and salience.
D. Bhandutia, S. Nayok
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Addition of a clinical pharmacist practitioner to an inpatient addiction triage team and related medication outcomes [PDF]
Mental Health Clinician, 2023 Introduction: At a Veterans Affairs Medical Center (VAMC), a clinical pharmacist practitioner (CPP) was added to an inpatient addiction triage team in August 2019 to provide education and recommendations regarding medications for alcohol use disorder ...
Kim Ehrhard, PharmD, BCPP +2 more
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