Results 21 to 30 of about 3,619 (165)
Calcium acamprosate: a triclinic polymorph [PDF]
Acta Crystallographica Section E, 2011 The title compound, poly[bis(μ3-4-acetamidopropanesulfonato)calcium], [Ca(C5H10NO4S)2]n, is a triclinic polymorph of the previously reported monoclinic structure [Toffoli et al. (1988). Acta Cryst. C44, 1493–1494].
Elisabetta Maccaroni +2 more
doaj +3 more sources
Combination of Drugs in the Treatment of Alcohol Use Disorder: A Meta-Analysis and Meta-Regression Study [PDF]
Brain SciencesBackground: Alcohol Use Disorder (AUD) is highly prevalent among substance use disorders worldwide and is characterized by a multifactorial pathophysiology.
João Vitor Guimarães Mandaji +6 more
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NMDA Receptors: Next therapeutic targets for Tinnitus? [PDF]
Biochemistry and Biophysics ReportsTinnitus, a common otological symptom, lacks clinically approved pharmacological treatments, highlighting an urgent unmet need. This review explores the potential role of NMDARs, key glutamate receptors in the auditory system, in tinnitus pathophysiology,
Chenhao Che, Yongzhen Wu, Shan Sun
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Pharmacology of Acamprosate: An Overview [PDF]
CNS Drug Reviews, 2003 ABSTRACTIn the last years important advances have been made in the development of drugs for the treatment of alcohol addiction. Acamprosate (calcium bis‐acetylhomotaurine) is one of the better established drugs in this field on the European market. This review focuses first on the pharmacokinetics of acamprosate.
Zornoza Sabina, Teodoro +3 more
openaire +3 more sources
Pharmacogenomics of alcohol addiction: Personalizing pharmacologic treatment of alcohol dependence [PDF]
Hospital Pharmacology, 2014 Alcohol dependence is a serious psychiatric disorder with harmful physical, mental and social consequences, and a high probability of a chronic relapsing course. The field of pharmacologic treatment of alcohol dependence and craving is expanding rapidly;
Ragia Georgia, Manolopoulos Vangelis G.
doaj +1 more source
Brain Sciences, 2022 Background: Although Alcohol Use Disorder (AUD) is highly prevalent worldwide, treating this condition remains challenging. Further, potential treatments for AUD do not fully address alcohol-induced neuroadaptive changes.
Luiza Florence +10 more
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The use of medications approved for alcohol use disorders in Italy
Frontiers in Public Health, 2023 BackgroundItaly has the highest per capita alcohol consumption among European countries. Several pharmacological treatments for alcohol use disorders (AUDs) are currently available in Italy, but no consumption data are available.
Filomena Fortinguerra +2 more
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PLoS ONE, 2022 AimThe current research aims to systematically review the rates of adherence reported in randomised controlled clinical trials of acamprosate. It also sought to determine the reliability of the adherence monitoring and measurement methods used in these ...
Kim Donoghue +3 more
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Safety and Efficacy of Acamprosate for the Treatment of Alcohol Dependence
Substance Abuse: Research and Treatment, 2013 Acamprosate (calcium acetylhomotaurine) is an amino acid modulator that has displayed efficacy in some clinical trials in reducing craving and promoting abstinence in alcohol dependent patients following detoxification.
Stephanie L. Yahn +2 more
doaj +1 more source
Journal of Neurodevelopmental Disorders, 2017 Background Fragile X Syndrome (FXS) occurs as a result of a silenced fragile X mental retardation 1 gene (FMR1) and subsequent loss of fragile X mental retardation protein (FMRP) expression.
Tori L. Schaefer +10 more
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