Results 91 to 100 of about 32,441 (268)

[Acanthamoeba keratitis].

open access: yesNederlands tijdschrift voor geneeskunde, 1996
Three patients, women aged 69, 25 and 30 years, with refractory keratitis were found to have a rare infection with Acanthamoeba. All wore soft contact lenses. The frequency of Acanthamoeba keratitis increased in recent years. At present, an efficacious antiprotozoal therapy is available, for instance in the form of polyhexamethylene biguanide and ...
Eggink, C.A.   +3 more
openaire   +2 more sources

What We Can Do in Infectious Keratitis, Except for Conventional Antimicrobial‐Based Therapies: Major Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Infectious keratitis (IK) is classified as a critical ophthalmic emergency, with the potential to result in vision‐impairing complications. The treatment approach involves the use of pharmacological antimicrobial agents in combination with surgical interventions.
Kasra Cheraqpour
wiley   +1 more source

Supercationic Poly(Hexamethylene Biguanide)‐Derived Carbon Dots for Combating Multidrug‐Resistant Bacterial Keratitis

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
This research introduces poly(hexamethylene biguanide)‐derived carbon dots (P‐CDs) as a novel antibacterial agent for combating multidrug‐resistant bacterial keratitis. P‐CDs exhibit potent activity against resistant pathogens, including MRSA and MRPA. In vivo results confirm their superior therapeutic efficacy over standard antibiotics, alongside the ...
Wenjie Fan   +8 more
wiley   +1 more source

Effective targeting of pathogenic Acanthamoeba castellanii of the T4 genotype using nano-formulations of Quercetin [PDF]

open access: yes
The incidence of infections caused by pathogenic Acanthamoeba is increasing, yet the prognosis continues to be poor. Acanthamoeba spp. are responsible for causing a blinding keratitis and a fatal granulomatous amoebic encephalitis. Due to limited options
Siddiqui, R.   +7 more
core   +1 more source

Repurposing Drugs as Bacteroides fragilis BFT‐3 Inhibitors in the Animal Infection Model Galleria mellonella

open access: yesAnnals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.
This work establishes a newly developed Galleria mellonella infection model as a powerful, ethical platform for studying Bacteroides fragilis pathogenesis and therapy. Leveraging this model, the study identifies MOA4 as a potent BFT‐3 inhibitor that improves host survival, increases bacterial clearance, and synergizes with antibiotics without toxicity.
Ana Jiménez‐Alesanco   +6 more
wiley   +1 more source

Species Identification of Acanthamoeba Strains Isolated from Patients Referring to Farabi Eye Reference Center Using PCR-RFLP Method

open access: yesJournal of Medical Microbiology and Infectious Diseases, 2014
Introduction: Acanthamoeba is an opportunistic protist, which is ubiquitously distributed in the environment. Infection with Acanthamoeba spp. poses threat to human health, such as, Acanthamoeba keratitis (AK) that is a vision-threatening infection of ...
Mir Mostafa Ghamilouie   +2 more
doaj  

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov   +8 more
wiley   +1 more source

The pathogenesis of Acanthamoeba infections: current status and future implications

open access: yes, 2004
Acanthamoeba are opportunistic protozoan parasites that can cause painful, visionthreatening keratitis. However the pathogenesis and pathophysiology of Acanthamoeba keratitis remain incompletely understood. Most cases of Acanthamoeba keratitis develop
Khan, Naveed Ahmed
core  

Acanthamoeba and the bacterial pathogen interactions [PDF]

open access: yes, 2015
The present study investigates Acanthamoeba-bacteria interaction and how this relation can influence human health aiming at the influence of bacteria on Acanthamoeba in terms of their isolation and diversity, and the effect of Acanthamoeba on bacteria ...
Asif, Muhammad
core  

In vitro Effect of Monosaccharides on the Virulence of Acanthamoeba Isolated from Patients with Amoebic Keratitis

open access: yesپزشکی بالینی ابن سینا, 2007
Introduction & Objective: Acanthamoeba is free-living amoeba that is found in soil, water, air as well as in human pharynx. Acanthamoeba is causative agent of granulomatose amoebic encephalitis (GAE) in immunosuppressed and AIDS individuals and amoebic ...
Yahya Maoofi   +3 more
doaj  

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