Results 71 to 80 of about 32,468 (218)

Supercationic Poly(Hexamethylene Biguanide)‐Derived Carbon Dots for Combating Multidrug‐Resistant Bacterial Keratitis

open access: yesSmall Structures, Volume 7, Issue 3, March 2026.
This research introduces poly(hexamethylene biguanide)‐derived carbon dots (P‐CDs) as a novel antibacterial agent for combating multidrug‐resistant bacterial keratitis. P‐CDs exhibit potent activity against resistant pathogens, including MRSA and MRPA. In vivo results confirm their superior therapeutic efficacy over standard antibiotics, alongside the ...
Wenjie Fan   +8 more
wiley   +1 more source

Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension [PDF]

open access: yes, 2004
Both the Arp2/3 complex and cofilin are believed to be important for the generation of protrusive force at the leading edge; however, their relative contributions have not been explored in vivo.
Bailly, M.   +3 more
core   +1 more source

Characterisation of sterol biosynthesis and validation of 14α-demethylase as a drug target in Acanthamoeba

open access: yesScientific Reports, 2017
The soil amoebae Acanthamoeba causes Acanthamoeba keratitis, a severe sight-threatening infection of the eye and the almost universally fatal granulomatous amoebic encephalitis. More effective treatments are required.
Scott Thomson   +5 more
doaj   +1 more source

Acanthamoeba Keratitis and Acanthamoeba Conjunctivitis: A Case Report

open access: yesIranian Journal of Parasitology, 2020
Acanthamoeba species are vision-threatening agents by causing cornea infections known as Acanthamoeba keratitis. A 5 year-old kid with the complaints of erythema, eyelid edema, inflammation, limitation of eye movements in the right eye, and having no history of wearing contact lenses or trauma, was diagnosed of Acanthamoeba conjunctivitis through ...
Tüzemen, NAZMİYE ÜLKÜ   +3 more
openaire   +5 more sources

Repurposing Drugs as Bacteroides fragilis BFT‐3 Inhibitors in the Animal Infection Model Galleria mellonella

open access: yesAnnals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.
This work establishes a newly developed Galleria mellonella infection model as a powerful, ethical platform for studying Bacteroides fragilis pathogenesis and therapy. Leveraging this model, the study identifies MOA4 as a potent BFT‐3 inhibitor that improves host survival, increases bacterial clearance, and synergizes with antibiotics without toxicity.
Ana Jiménez‐Alesanco   +6 more
wiley   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov   +8 more
wiley   +1 more source

Primary Amoebic (Naegleria fowleri) Meningoencephalitis Presenting as Status Epilepticus [PDF]

open access: yes, 2011
Primary amebic meningoencephalitis (PAM) is a rare entity. Usual presenting features are fever, headache and seizures with meningeal signs and this disease carries high mortality rate.
Bharti, V   +5 more
core   +1 more source

The Characterisation of an Adrenergic Signalling System Involved in the Encystment of the Ocular Pathogen Acanthamoeba spp. [PDF]

open access: yes, 2016
The aim of this study was to identify and characterise the receptor system involved in controlling encystment in Acanthamoeba using specific agonists and antagonists and to examine whether endogenous stores of catecholamines are produced by the organism.
Abel   +39 more
core   +1 more source

Microbial Distributions Across Wide‐Ranging Temperature Gradients of Hot Springs in Thailand: A Review of 35 Years of Research on Hot Spring‐Associated Microorganisms

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 1, February 2026.
This review article summarised 35 years of research on microbial distributions (bacteria, archaea and microbial eukaryotes) across wide‐ranging hot spring temperatures in Thailand, including the overall research progression, scopes and methodologies of previous studies.
C. Sriaporn   +5 more
wiley   +1 more source

Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family. [PDF]

open access: yes, 1993
A polymerase chain reaction strategy was devised to identify new members of the mammalian myosin I family of actin-based motors. Using cellular RNA from mouse granular neurons and PC12 cells, we have cloned and sequenced three 1.2-kb polymerase chain ...
Greene, LA, Joyce, MP, Sherr, EH
core  

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