Results 1 to 10 of about 10,570,776 (162)

Potential anti-amoebic effects of synthetic 1,4-benzothiazine derivatives against Acanthamoeba castellanii [PDF]

open access: yesHeliyon
A rare but lethal central nervous system disease known as granulomatous amoebic encephalitis (GAE) and potentially blinding Acanthamoeba keratitis are diseases caused by free-living Acanthamoeba.
Alishba   +7 more
doaj   +6 more sources

The Anti-Amoebic Activity of a Peptidomimetic against Acanthamoeba castellanii [PDF]

open access: yesMicroorganisms, 2022
Acanthamoeba is a free-living protozoan known to cause keratitis most commonly, especially among contact lens wearers. Treatment of Acanthamoeba keratitis is challenging as Acanthamoeba can encyst from the active form, a trophozoite, into a hibernating ...
Hari Kumar Peguda   +5 more
doaj   +3 more sources

Riluzole, a Derivative of Benzothiazole as a Potential Anti-Amoebic Agent against Entamoeba histolytica

open access: yesPharmaceuticals, 2023
Amoebiasis is produced by the parasite Entamoeba histolytica; this disease affects millions of people throughout the world who may suffer from amoebic colitis or amoebic liver abscess.
Maritza Velásquez-Torres   +9 more
doaj   +2 more sources

Repurposing CNS drugs Zonisamide and Perampanel conjugated with silver nanoparticles as an anti-amoebic agent in combating Granulomatous Amebic Encephalitis (GAE) and Primary Amebic Meningoencephalitis (PAM) infection caused by Acanthamoeba castellanii and Naegleria Fowleri [PDF]

open access: yesParasite Epidemiology and Control
Acanthamoeba castellanii (A. castellanii) and Naegleria fowleri (N. fowleri) are free-living amoebae that cause Granulomatous Amoebic Encephalitis (GAE) and Primary Amoebic Meningoencephalitis (PAM), respectively rare but often fatal central nervous ...
Devandran Apparasamy   +8 more
doaj   +2 more sources

Histone deacetylase inhibitors enhance the amoebicidal activity of amphotericin B against Naegleria fowleri [PDF]

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance
Naegleria fowleri is a free-living amoeba that causes a rare but almost always fatal brain infection known as primary amoebic meningoencephalitis (PAM). Although amphotericin B (AmB) is considered the primary treatment for PAM, it is often recommended in
Hae-Ahm Lee   +4 more
doaj   +2 more sources

Selected Gut Bacteria from Water Monitor Lizard Exhibit Effects against Pathogenic Acanthamoeba castellanii Belonging to the T4 Genotype

open access: yesMicroorganisms, 2023
Water monitor lizards (WMLs) reside in unhygienic and challenging ecological surroundings and are routinely exposed to various pathogenic microorganisms. It is possible that their gut microbiota produces substances to counter microbial infections.
Noor Akbar   +6 more
doaj   +1 more source

PREPARATION AND EVALUATION OF COMPRESSED COATED TABLETS USING POLYELECTROLYTE COMPLEX FOR TARGETED DELIVERY OF ANTI-AMOEBIC DRUG [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 2022
An unwanted absorption of anti-amoebic drug at upper gastrointestinal tract (GIT) causes numerous side effects and requires higher doses to get therapeutic effect.
Vaibhav Tiwari   +5 more
doaj   +1 more source

Antiamoebic Properties of Laboratory and Clinically Used Drugs against Naegleria fowleri and Balamuthia mandrillaris

open access: yesAntibiotics, 2022
Naegleria fowleri and Balamuthia mandrillaris are pathogenic free-living amoebae that infect the central nervous system with over 95% mortality rates.
Ruqaiyyah Siddiqui   +6 more
doaj   +1 more source

Antiamoebic Properties of Ceftriaxone and Zinc-Oxide–Cyclodextrin-Conjugated Ceftriaxone

open access: yesAntibiotics, 2022
Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent.
Zinb Makhlouf   +6 more
doaj   +1 more source

Nanocarrier Drug Conjugates Exhibit Potent Anti-Naegleria fowleri and Anti-Balamuthia mandrillaris Properties

open access: yesDiseases, 2023
Given the opportunity and access, pathogenic protists (Balamuthia mandrillaris and Naegleria fowleri) can produce fatal infections involving the central nervous system.
Ruqaiyyah Siddiqui   +7 more
doaj   +1 more source

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