All you need is fungi: Exploring secondary metabolites as a source of novel amoebicidal agents [PDF]
Genetics and Molecular BiologyFree-living amoebae (FLAs) of the genus Acanthamoeba are opportunistic protozoa found in diverse environments. They can cause granulomatous amoebic encephalitis, especially in immunocompromised individuals, and Acanthamoeba keratitis, a painful corneal ...
Maria Eduarda Deluca João +7 more
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Phragmites australis (Cav.) Trin. ex Steud. Extract Induces Apoptosis-like Programmed Cell Death in Acanthamoeba castellanii Trophozoites [PDF]
Plants, 2022 Acanthamoeba keratitis (AK) is an infectious ocular disease which is difficult to diagnose correctly and cure. Development of an effective and safe therapeutic drug for AK is needed.
Hương-Giang Lê +11 more
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Iris setosa Pall. ex Link Extract Reveals Amoebicidal Activity against Acanthamoeba castellanii and Acanthamoeba polyphaga with Low Toxicity to Human Corneal Cells [PDF]
MicroorganismsAcanthamoeba keratitis (AK) is a sight-threatening and difficult-to-treat ocular infection. The significant side effects of current AK treatments highlight the urgent need to develop a safe and effective AK medication.
Hương Giang Lê +7 more
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Molecules, 2015 Four new hydrazones were synthesized by the condensation of the selected hydrazine and the appropriate nitrobenzaldehyde. A complete characterization was done employing 1H- and 13C-NMR, electrochemical techniques and theoretical studies.
Yanis Toledano-Magaña +2 more
exaly +3 more sources
Repurposing CNS drugs Zonisamide and Perampanel conjugated with silver nanoparticles as an anti-amoebic agent in combating Granulomatous Amebic Encephalitis (GAE) and Primary Amebic Meningoencephalitis (PAM) infection caused by Acanthamoeba castellanii and Naegleria Fowleri [PDF]
Parasite Epidemiology and ControlAcanthamoeba castellanii (A. castellanii) and Naegleria fowleri (N. fowleri) are free-living amoebae that cause Granulomatous Amoebic Encephalitis (GAE) and Primary Amoebic Meningoencephalitis (PAM), respectively rare but often fatal central nervous ...
Devandran Apparasamy +8 more
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The Amoebicidal Activity of Diferrocenyl Derivatives: A Significant Dependence on the Electronic Environment [PDF]
Molecules, 2023 Amoebiasis is the second leading cause of death worldwide associated with parasitic disease and is becoming a critical health problem in low-income countries, urging new treatment alternatives.
Yanis Toledano-Magaña +6 more
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Selected Gut Bacteria from Water Monitor Lizard Exhibit Effects against Pathogenic Acanthamoeba castellanii Belonging to the T4 Genotype [PDF]
Microorganisms, 2023 Water monitor lizards (WMLs) reside in unhygienic and challenging ecological surroundings and are routinely exposed to various pathogenic microorganisms. It is possible that their gut microbiota produces substances to counter microbial infections.
Noor Akbar +6 more
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Expanding the antiprotozoal activity and the mechanism of action of n-butyl and iso-butyl ester of quinoxaline-1,4-di-N-oxide derivatives against Giardia lamblia, Trichomonas vaginalis, and Entamoeba histolytica. An in vitro and in silico approach [PDF]
Journal of Enzyme Inhibition and Medicinal ChemistryIn this study, n-butyl and iso-butyl quinoxaline-7-carboxylate-1,4-di-N-oxide derivatives were evaluated in vitro against Giardia lamblia (G. lamblia), Trichomonas vaginalis (T. vaginalis), and Entamoeba histolytica (E. histolytica).
Alonzo González-González +13 more
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Correction: The amoebicidal effect of Torreya nucifera extract on Acanthamoeba lugdunensis. [PDF]
PLoS ONE, 2023 [This corrects the article DOI: 10.1371/journal.pone.0281141.].
Min Seung Kang +4 more
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Amoebicidal, anti-adhesive, and low-cytotoxic effects of Mangifera indica L. leaf extract against ocular Acanthamoeba spp.: First evidence supporting plant-based therapeutic potential [PDF]
Veterinary WorldBackground and Aim: Acanthamoeba spp. is free-living protozoa capable of causing severe infections, notably Acanthamoeba keratitis, which is difficult to manage due to cyst resistance and the cytotoxicity of current treatments.
Diana Mendonça +15 more
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