GalNAc Carbohydrate Prevents the Formation of Neutrophil Extracellular Traps and Increase Myeloperoxidase Enzyme Activity in Interactions of Neutrophils and Entamoeba histolytica Preincubated With GalNAc. [PDF]
Biomed Res IntDuring amoebic infection, neutrophils are the first cells of the immune system to interact with trophozoites of Entamoeba histolytica, initiating amoebicidal activity. Different lectins and carbohydrates can participate in the mechanism of adhesion between E.
Levaro-Loquio D +8 more
europepmc +2 more sources
Antibiotics, 2022 We examined the antiamoebic effect of several imidazothiazole derivatives on Acanthamoeba castellanii of the T4 genotype. Trypan blue exclusion assays and haemocytometer counting were used to determine the reduction in A.
Noor Akbar +8 more
doaj +1 more source
Antibiotics, 2022 Naegleria fowleri and Balamuthia mandrillaris are pathogenic free-living amoebae that infect the central nervous system with over 95% mortality rates.
Ruqaiyyah Siddiqui +6 more
doaj +1 more source
Experimental and Theoretical Evidence on the Amoebicidal Activity of Synthesized tRNA-Palmitic Acid Esters [PDF]
Iranian Journal of Chemistry & Chemical EngineeringSynthesis of tRNA-palmitic acid esters was carried out in dimethyl sulfoxide (DMSO) and tert-butanol, %20 and %80 (v/v), respectively, for 24h at 55oC.
Aysun Aksu +5 more
doaj +2 more sources
Imidazothiazole Derivatives Exhibited Potent Effects against Brain-Eating Amoebae
Antibiotics, 2022 Naegleria fowleri (N. fowleri) is a free-living, unicellular, opportunistic protist responsible for the fatal central nervous system infection, primary amoebic meningoencephalitis (PAM).
Ruqaiyyah Siddiqui +8 more
doaj +1 more source
<i>Mentha rotundifolia</i>, a Source of Amoebicidal Agents Against <i>Naegleria fowleri</i>. [PDF]
Int J Mol SciCurrent therapies for Primary Amoebic Meningoencephalitis (PAM) present several limitations; consequently, there is an urgent need to develop new therapeutic agents.
Ben Youssef M +9 more
europepmc +2 more sources
Amoebicidal Activity of Poly-Epsilon-Lysine Functionalized Hydrogels [PDF]
, 2022 PURPOSE. To determine the amoebicidal activity of functionalized poly-epsilon-lysine hydrogels (pϵK+) against Acanthamoeba castellanii. METHODS. A. castellanii trophozoites and cysts were grown in the presence of p?K solution (0-2.17 mM), pϵK or pϵK ...
Horsburgh, MJ +7 more
core +1 more source
Antiamoebic Properties of Ceftriaxone and Zinc-Oxide–Cyclodextrin-Conjugated Ceftriaxone
Antibiotics, 2022 Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent.
Zinb Makhlouf +6 more
doaj +1 more source
Phenotypic assay for cytotoxicity assessment of Balamuthia mandrillaris against human neurospheroids
Frontiers in Microbiology, 2023 IntroductionThe phenotypic screening of drugs against Balamuthia mandrillaris, a neuropathogenic amoeba, involves two simultaneous phases: an initial step to test amoebicidal activity followed by an assay for cytotoxicity to host cells.
Narisara Whangviboonkij +7 more
doaj +1 more source
The High Potential of ε‐Poly‐l‐Lysine for the Development of Antimicrobial Biomaterials
Advanced NanoBiomed Research, Volume 3, Issue 12, December 2023., 2023 ε‐poly‐l‐lysine (ε‐PLL) is a natural polypeptide originating from bacteria with strong antifungal and antibacterial properties. ε‐PLL is highly used to develop antimicrobial materials and as an alternative to antibiotics as its mechanism of action reduces the bacterial resistance risk compared with antibiotics.
Eloïse Lebaudy +4 more
wiley +1 more source