Results 21 to 30 of about 999 (169)
Antiamoebic Properties of Ceftriaxone and Zinc-Oxide–Cyclodextrin-Conjugated Ceftriaxone
Antibiotics, 2022 Acanthamoeba castellanii is a ubiquitous free-living amoeba capable of instigating keratitis and granulomatous amoebic encephalitis in humans. Treatment remains limited and inconsistent.
Zinb Makhlouf +6 more
doaj +1 more source
Novel Azoles as Antiparasitic Remedies against Brain-Eating Amoebae
Antibiotics, 2020 Balamuthia mandrillaris and Naegleria fowleri are opportunistic protozoan pathogens capable of producing infection of the central nervous system with more than 95% mortality rate.
Ayaz Anwar +8 more
doaj +1 more source
Scientific Reports, 2022 Amoebae from the genus Acanthamoeba are important pathogens responsible for severe illnesses in humans such as Acanthamoeba keratitis and granulomatous amoebic encephalitis. In the last few decades, AK diagnoses have steadily increased.
P. López-Barona +8 more
doaj +1 more source
Phenotypic assay for cytotoxicity assessment of Balamuthia mandrillaris against human neurospheroids
Frontiers in Microbiology, 2023 IntroductionThe phenotypic screening of drugs against Balamuthia mandrillaris, a neuropathogenic amoeba, involves two simultaneous phases: an initial step to test amoebicidal activity followed by an assay for cytotoxicity to host cells.
Narisara Whangviboonkij +7 more
doaj +1 more source
The High Potential of ε‐Poly‐l‐Lysine for the Development of Antimicrobial Biomaterials
Advanced NanoBiomed Research, Volume 3, Issue 12, December 2023., 2023 ε‐poly‐l‐lysine (ε‐PLL) is a natural polypeptide originating from bacteria with strong antifungal and antibacterial properties. ε‐PLL is highly used to develop antimicrobial materials and as an alternative to antibiotics as its mechanism of action reduces the bacterial resistance risk compared with antibiotics.
Eloïse Lebaudy +4 more
wiley +1 more source
Carbosilane dendritic nanostructures, highly versatile platforms for pharmaceutical applications
WIREs Nanomedicine and Nanobiotechnology, Volume 15, Issue 3, May/June 2023., 2023 Carbosilane dendritic systems are unique tools for the therapy, prevention, and diagnosis of multiple diseases. They can be precisely designed for the specific purpose, thus maximizing the biological activity. Abstract Dendrimers are multifunctional molecules with well‐defined size and structure due to the step‐by‐step synthetic procedures required in ...
Francisco Javier de la Mata +5 more
wiley +1 more source
Synthesis and Evaluation of Novel DNA Minor Groove Binders as Antiamoebic Agents
Antibiotics, 2022 The free-living amoeba Acanthamoeba castellanii is responsible for the central nervous infection granulomatous amoebic encephalitis and sight-threatening infection Acanthamoeba keratitis.
Hasan Y. Alniss +7 more
doaj +1 more source
In vitro amoebicidal activity of immune cells [PDF]
Infection and Immunity, 1982 The amoebicidal activity of peripheral blood lymphocytes and spleen and peritoneal cells from hamsters vaccinated against or protected from hepatic amoebiasis and from those with hepatic amoebiasis was investigated. Peripheral blood lymphocytes and peritoneal and spleen cells from vaccinated or protected animals can kill trophozoites of Entamoeba ...
E, Ghadirian, E, Meerovitch
openaire +2 more sources
Journal of Parasitology Research, Volume 2023, Issue 1, 2023., 2023 Acanthamoeba griffini is known to cause amoebic keratitis (AK); its main causes are inadequate hygiene when contact lenses are handled and/or its prolonged use at night, as well as the use of contact lenses during underwater activities. The most used treatment for AK is the combination of propamidine isethionate combined with polyhexamethylene ...
Manuel Enrique Ávila-Blanco +6 more
wiley +1 more source
International Journal of Clinical Practice, Volume 75, Issue 10, October 2021., 2021 Abstract Aims To conduct a systematic review of the management of minor ailments by community pharmacists in developing countries, and to identify the specific minor ailments encountered, the medications recommended or requested and the information gathering and counselling practices.
Kazeem B. Yusuff +2 more
wiley +1 more source