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Anti-Amoebic Properties of Carbonyl Thiourea Derivatives [PDF]

open access: yesMolecules, 2014
Thiourea derivatives display a broad spectrum of applications in chemistry, various industries, medicines and various other fields. Recently, different thiourea derivatives have been synthesized and explored for their anti-microbial properties.
Maizatul Akma Ibrahim   +2 more
doaj   +4 more sources

Riluzole, a Derivative of Benzothiazole as a Potential Anti-Amoebic Agent against Entamoeba histolytica [PDF]

open access: yesPharmaceuticals, 2023
Amoebiasis is produced by the parasite Entamoeba histolytica; this disease affects millions of people throughout the world who may suffer from amoebic colitis or amoebic liver abscess.
Maritza Velásquez-Torres   +9 more
doaj   +2 more sources

The Anti-Amoebic Activity of a Peptidomimetic against Acanthamoeba castellanii [PDF]

open access: yesMicroorganisms, 2022
Acanthamoeba is a free-living protozoan known to cause keratitis most commonly, especially among contact lens wearers. Treatment of Acanthamoeba keratitis is challenging as Acanthamoeba can encyst from the active form, a trophozoite, into a hibernating ...
Hari Kumar Peguda   +5 more
doaj   +2 more sources

Efficacy of Off-Label Anti-Amoebic Agents to Suppress Trophozoite Formation of Acanthamoeba spp. on Non-Nutrient Agar Escherichia Coli Plates [PDF]

open access: yesMicroorganisms, 2022
Acanthamoeba keratitis (AK) is a dangerous infectious disease, which is associated with a high risk of blindness for the infected patient, and for which no standard therapy exists thus far.
Vithusan Muthukumar   +10 more
doaj   +2 more sources

Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes [PDF]

open access: yesFrontiers in Microbiology, 2023
Acanthamoeba species, Naegleria fowleri, and Balamuthia mandrillaris are opportunistic pathogens that cause a range of brain, skin, eye, and disseminated diseases in humans and animals.
Lori Ferrins   +35 more
doaj   +2 more sources

Antineoplastic kinase inhibitors: A new class of potent anti-amoebic compounds. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2021
Entamoeba histolytica is a protozoan parasite which infects approximately 50 million people worldwide, resulting in an estimated 70,000 deaths every year. Since the 1960s E. histolytica infection has been successfully treated with metronidazole. However,
Conall Sauvey   +4 more
doaj   +2 more sources

Ginsenosides Rb3 and Rc Exhibit Anti-Amoebic Activities Against Naegleria fowleri, the Etiological Agent of Primary Amoebic Meningoencephalitis [PDF]

open access: yesPharmaceuticals
Background/Objectives: Naegleria fowleri is an opportunistic pathogen causing primary amoebic meningoencephalitis (PAM), a fatal neuroinflammatory disease with a high mortality rate of over 97%, in humans.
Thu Hằng Nguyễn   +4 more
doaj   +2 more sources

Repurposing CNS drugs Zonisamide and Perampanel conjugated with silver nanoparticles as an anti-amoebic agent in combating Granulomatous Amebic Encephalitis (GAE) and Primary Amebic Meningoencephalitis (PAM) infection caused by Acanthamoeba castellanii and Naegleria Fowleri [PDF]

open access: yesParasite Epidemiology and Control
Acanthamoeba castellanii (A. castellanii) and Naegleria fowleri (N. fowleri) are free-living amoebae that cause Granulomatous Amoebic Encephalitis (GAE) and Primary Amoebic Meningoencephalitis (PAM), respectively rare but often fatal central nervous ...
Devandran Apparasamy   +8 more
doaj   +2 more sources

Anti-amoebic and biocompatible properties of nephrite-embedded contact lenses [PDF]

open access: yesScientific Reports
Acanthamoeba keratitis remains a severe complication of contact lens (CL) wear, and preventing trophozoite adhesion to the lens surface is a critical step in preventing infection.
Ji Ho Park   +8 more
doaj   +2 more sources

Potential anti-amoebic effects of synthetic 1,4-benzothiazine derivatives against Acanthamoeba castellanii [PDF]

open access: yesHeliyon
A rare but lethal central nervous system disease known as granulomatous amoebic encephalitis (GAE) and potentially blinding Acanthamoeba keratitis are diseases caused by free-living Acanthamoeba.
Alishba   +7 more
doaj   +2 more sources

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