Saudi Pharmaceutical Journal, 2023 Amoebae of the genus Acanthamoeba can cause diseases such as amoebic keratitis and granulomatous amoebic encephalitis. Until now, treatment options for these diseases have not been fully effective and have several drawbacks.
Khairunisa Mohd Zamli +6 more
doaj +3 more sources
Corrigendum: Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes [PDF]
Frontiers in Microbiology, 2023 Lori Ferrins +35 more
doaj +2 more sources
High-throughput phenotypic screen identifies a new family of potent anti-amoebic compounds. [PDF]
PLoS One, 2023 Entamoeba histolytica is a disease-causing parasitic amoeba which affects an estimated 50 million people worldwide, particularly in socioeconomically vulnerable populations experiencing water sanitation issues. Infection with E . histolytica
Sauvey C +5 more
europepmc +5 more sources
Bioassay-guided fractionation of extracts from Codiaeum variegatum against Entamoeba histolytica discovers compounds that modify expression of ceramide biosynthesis related genes. [PDF]
PLoS Neglected Tropical Diseases, 2014 Leaves of Codiaeum variegatum ("garden croton") are used against bloody diarrhoea by local populations in Cameroon. This study aims to search for the active components from C.
Emmanuel Mfotie Njoya +7 more
doaj +1 more source
Antimicrobial activity of some isatin-3--thiosemicarbazone complexes [PDF]
Journal of the Serbian Chemical Society, 2008 Isatin-3-thiosemicarbazone complexes with Co(II), Ni(II), Cu(II), Zn(II), Hg(II) and Pd(II) were synthesized and evaluated for their antimicrobial activity against 7 pathogenic bacteria and 4 fungi. The complexes have an enhanced activity compared to the
SANDRA S. KONSTANTINOVIC +3 more
doaj +3 more sources
The Effect of Anti-Amoebic Agents and Ce6-PDT on Acanthamoeba castellanii Trophozoites and Cysts, In Vitro. [PDF]
Transl Vis Sci Technol, 2020 The purpose of this study was to analyze the concentration-dependent effects of biguanides (polyhexamethylene biguanide [PHMB], chlorhexidine [CH]); diamidines (hexamidine-diisethionate [HD], propamidine-isethionate [PD], dibromopropamidine-diisethionate [DD]); natamycin (NM); miltefosine (MF); povidone iodine (PVPI), and chlorin e6 PDT on Acanthamoeba
Shi L +10 more
europepmc +3 more sources
Antiamoebic Properties of Metabolites against Naegleria fowleri and Balamuthia mandrillaris
Antibiotics, 2022 Naegleria fowleri and Balamuthia mandrillaris are free-living, opportunistic protists, distributed widely in the environment. They are responsible for primary amoebic meningoencephalitis (PAM) and granulomatous amoebic encephalitis (GAE), the fatal ...
Ruqaiyyah Siddiqui +7 more
doaj +1 more source
Imidazothiazole Derivatives Exhibited Potent Effects against Brain-Eating Amoebae
Antibiotics, 2022 Naegleria fowleri (N. fowleri) is a free-living, unicellular, opportunistic protist responsible for the fatal central nervous system infection, primary amoebic meningoencephalitis (PAM).
Ruqaiyyah Siddiqui +8 more
doaj +1 more source
Diseases, 2023 Given the opportunity and access, pathogenic protists (Balamuthia mandrillaris and Naegleria fowleri) can produce fatal infections involving the central nervous system.
Ruqaiyyah Siddiqui +7 more
doaj +1 more source
Anti-amoebic potential of azole scaffolds and nanoparticles against pathogenic Acanthamoeba [PDF]
Acta Tropica, 2020 Acanthamoeba spp. are free living amoeba (FLA) which are widely distributed in nature. They are opportunistic parasites and can cause severe infections to the eye, skin and central nervous system. The advances in drug discovery and modifications in the chemotherapeutic agents have shown little improvement in morbidity and mortality rates associated ...
Shweta, Walvekar +6 more
openaire +2 more sources