Results 41 to 50 of about 36,777 (257)

Silver Nanoparticles as a Novel Potential Preventive Agent against Acanthamoeba Keratitis

Pathogens, 2020
Free living, cosmopolitan amoebae from Acanthamoeba genus present a serious risk to human health. As facultative human parasites, these amoebae may cause Acanthamoeba keratitis (AK).
E. Hendiger, Marcin Padzik, I. Sifaoui, M. Reyes-Batlle, Atteneri López-Arencibia, Aitor Rizo-Liendo, Carlos J. Bethencourt-Estrella, Desirée San Nicolás-Hernández, Olfa Chiboub, R. Rodríguez-Expósito, M. Grodzik, Anna Pietruczuk-Padzik, Karolina Stępień, G. Olędzka, L. Chomicz, J. Piñero, J. Lorenzo-Morales   +16 more
semanticscholar   +1 more source

Acanthamoeba keratitis: confirmation of the UK outbreak and a prospective case-control study identifying contributing risk factors

British Journal of Ophthalmology, 2018
Background/aims Acanthamoeba keratitis (AK) is a chronic debilitating corneal infection principally affecting contact lens (CL) users. Studies were designed to test claims that the UK incidence may have increased in 2012–2014 and to evaluate potential ...
Nicole A. Carnt, J. Hoffman, S. Verma, S. Hau, C. Radford, D. Minassian, J. Dart   +6 more
semanticscholar   +1 more source

Metronidazole conjugated magnetic nanoparticles loaded with amphotericin B exhibited potent effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype

AMB Express, 2020
Acanthamoeba castellanii can cause granulomatous amoebic encephalitis and Acanthamoeba keratitis. Currently, no single drug has been developed to effectively treat infections caused by Acanthamoeba.
Sumayah Abdelnasir, Ayaz Anwar, Muhammad Kawish, Areeba Anwar, M. Shah, R. Siddiqui, N. Khan   +6 more
semanticscholar   +1 more source

Current report on the prevalence of free-living amoebae (FLA) in natural hot springs: a systematic review

Journal of Water and Health, 2021
The occurrence of potentially pathogenic free-living amoebae (FLA) in natural hot springs is considered a public health concern. FLAs are known to cause serious health outcomes to a wide spectrum of mammalian hosts. The present study aimed to provide the
Mary Rachael Leigh Fabros, Xyleen Rianne Shae Diesta, John Anthony Oronan, Kim Sofia Verdejo, Joe-Anna Sheilla Marie Garcia, Ma. Sophia Romey, Giovanni De Jesus Milanez   +6 more
doaj   +1 more source

The Antifungal Drug Isavuconazole Is both Amebicidal and Cysticidal against Acanthamoeba castellanii

Antimicrobial Agents and Chemotherapy, 2020
Current treatments for Acanthamoeba keratitis rely on a combination of chlorhexidine gluconate, propamidine isethionate, and polyhexamethylene biguanide.
B. Shing, Seema Singh, L. Podust, J. McKerrow, A. Debnath   +4 more
semanticscholar   +1 more source

Comparative genomic analysis of Acanthamoeba from different sources and horizontal transfer events of antimicrobial resistance genes

mSphere
Acanthamoeba species are among the most common free-living amoeba and ubiquitous protozoa, mainly distributed in water and soil, and cause Acanthamoeba keratitis (AK) and severe visual impairment in patients.
Xinyi Ling, Xiaobin Gu, Yue Shen, Chunyan Fu, Yumei Zhou, Yiling Yin, Yanqiu Gao, Yiwei Zhu, Yongliang Lou, Meiqin Zheng   +9 more
doaj   +1 more source

Detection and Identification of Acanthamoeba and Other Nonviral Causes of Infectious Keratitis in Corneal Scrapings by Real-Time PCR and Next-Generation Sequencing-Based 16S-18S Gene Analysis

Journal of Clinical Microbiology, 2020
Acanthamoeba is a free-living amoeba of extensive genetic diversity. It may cause infectious keratitis (IK), which can also be caused by bacteria, fungi, and viruses. ABSTRACT Acanthamoeba is a free-living amoeba of extensive genetic diversity.
D. B. Holmgaard, Celine Barnadas, Seyed Hossein Mirbarati, L. O'Brien Andersen, H. Nielsen, C. R. Stensvold   +5 more
semanticscholar   +1 more source

A method for microbial decontamination of Acanthamoeba cultures using the peritoneal cavity of mice

Asian Pacific Journal of Tropical Biomedicine, 2015
Objective: To evaluate whether the inoculation of contaminated cultures in the peritoneal cavity of mice could implement decontamination of Acanthamoeba cultures.
Daniella de Sousa Mendes Moreira Alves, Rodrigo Gurgel-Gonçalves, Patrícia Albuquerque, César Augusto Cuba-Cuba, Maria Imaculada Muniz-Junqueira, Selma Aparecida Souza Kückelhaus   +5 more
doaj   +1 more source

Rare Infectious Diseases: Detection and Clinical Implications

iLABMED, EarlyView.
Rare infectious diseases are infections that are uncommon, have a low incidence, and are caused by newly emerging pathogens, cross‐species or ectopic infections, or host immunodeficiencies. The detection and diagnosis of rare infections is one of the main reasons for misdiagnosis and missed diagnosis.
Xin Qian, Yuxin Zhang, Yilin Ye, Qiange Lin, Junyou Lin, Xinrong Lu, Li Chen, Guiqin Sun   +7 more
wiley   +1 more source

Lethal encephalitis due to free-living amoebae in three members of a family, Tumbes, Peru

Revista Peruana de Medicina Experimental y Salud Pública, 2021
Free-living amoebas (FLA) are protozoan parasites that occasionally cause disease in humans after contact with contaminated water or soil. We describe a series of three cases of encephalitis in a family group with a fatal outcome that occurred in the ...
María Edith Solís-Castro
doaj   +1 more source