Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution. [PDF]
, 2020 The Hippo pathway is a central regulator of organ size and a key tumor suppressor via coordinating cell proliferation and death. Initially discovered in Drosophila, the Hippo pathway has been implicated as an evolutionarily conserved pathway in mammals ...
Chen, Yuxuan +7 more
core
The development of drugs against Acanthamoeba infections [PDF]
, 2016 For the past several decades, there has been little improvement in the morbidity and mortality associated with Acanthamoeba keratitis and Acanthamoeba encephalitis, respectively.
Aqeel, Yousuf +2 more
core +1 more source
Effect of environmental stress factors on the uptake and survival of Campylobacter jejuni in Acanthamoeba castellanii [PDF]
, 2012 Background Campylobacter jejuni is a major cause of bacterial food-borne illness in Europe and North America. The mechanisms allowing survival in the environment and transmission to new hosts are not well understood.
Bang, Dang Duong +4 more
core +3 more sources
Amoebicidal Effect of COVID Box Molecules against Acanthamoeba: A Study of Cell Death
PharmaceuticalsAcanthamoeba spp. can cause a sight threatening disease. At present, the current treatments used to treat Acanthamoeba spp. Infections, such as biguanide-based antimicrobials, remain inefficacious, with the appearance of resistant forms and high ...
Ines Sifaoui +5 more
doaj +1 more source
In vitro efficacy of clinically available drugs against growth and viability of Acanthamoeba castellanii keratitis isolate belonging to the T4 genotype [PDF]
, 2013 The effects of clinically available drugs targeting muscarinic cholinergic, adrenergic, dopaminergic, and serotonergic receptors; intracellular calcium levels and/or the function of calcium-dependent biochemical pathways; ion channels; and cellular pumps
Baig, Abdul Mannan +2 more
core +1 more source
Acanthamoeba induces cell-cycle arrest in host cells [PDF]
, 2004 Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alizadeh +41 more
core +1 more source
Anti-Amoebic Properties of Carbonyl Thiourea Derivatives
Molecules, 2014 Thiourea derivatives display a broad spectrum of applications in chemistry, various industries, medicines and various other fields. Recently, different thiourea derivatives have been synthesized and explored for their anti-microbial properties.
Maizatul Akma Ibrahim +2 more
doaj +1 more source
Effects of Mannose on Pathogenesis of Acanthamoeba castellanii
The Korean Journal of Parasitology, 2012 Acanthamoeba spp. are single-celled protozoan organisms that are widely distributed in the environment. In this study, to understand functional roles of a mannose-binding protein (MBP), Acanthamoeba castellanii was treated with methyl-alpha-D-mannopyranoside (mannose), and adhesion and cytotoxicity of the amoeba were analyzed.
Yoo, Kyung-Tae, Jung, Suk-Yul
openaire +2 more sources
Data in Brief, 2014 This article describes and directly links to 1033 Acanthamoeba castellanii mitochondrial protein sequences. Of these, 709 are supported by Mass Spectrometry (MS) data (676 nucleus-encoded and 33 mitochondrion-encoded). Two of these entries are previously
Ryan M.R. Gawryluk +3 more
doaj +1 more source
Photoinhibition of Growth in Acanthamoeba castellanii Cultures [PDF]
Journal of Bacteriology, 1970 Light from 350 to 680 nm at intensities up to 1.62 × 10 5 ergs per sec per cm 2 slowed exponential growth and lowered the maximum yield in axenic cultures of Acanthamoeba castellanii . Photoinhibition was a linear function of light intensity up to 1.25 × 10
openaire +2 more sources