The pathogenesis of Acanthamoeba infections: current status and future implications [PDF]
, 2004 Acanthamoeba are opportunistic protozoan parasites that can cause painful, visionthreatening keratitis. However the pathogenesis and pathophysiology of Acanthamoeba keratitis remain incompletely understood. Most cases of Acanthamoeba keratitis develop
Khan, Naveed Ahmed
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Isolation of Acanthamoeba isolates belonging to T2, T3, T4 and T7 genotypes from environmental samples in Ankara, Turkey [PDF]
, 2004 Acanthamoeba keratitis is a blinding infection that is becoming increasingly important in human health. Early diagnosis is a prerequisite for successful treatment and requires identification of Acanthamoeba at the genotypic level.
Khan, Naveed Ahmed +4 more
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The effect of surface treatment of silicone hydrogel contact lenses on the attachment of Acanthamoeba castellanii trophozoites [PDF]
, 2009 Aims to determine if plasma surface treatment of Focus Night & Day silicone hydrogel contact lenses affects the attachment of Acanthamoeba. Unworn lotrafilcon A contact lenses with (Focus Night & Day) and with out surface treatment and Acuvue ...
Tomlinson, Alan, Beattie, Tara K.
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Molecular basis for resistance of acanthamoeba tubulins to all major classes of antitubulin compounds [PDF]
, 2008 Tubulin is essential to eukaryotic cells and is targeted by several antineoplastics, herbicides, and antimicrobials. We demonstrate that Acanthamoeba spp.
Henriquez, Fiona L. +4 more
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Induced encystment improves resistance to preservation and storage of Acanthamoeba castellanii [PDF]
, 2008 Several conditions that allow the preservation, storage and rapid, efficient recovery of viable Acanthamoeba castellanii organisms were investigated. The viability of trophozoites (as determined by time to confluence) significantly declined over a period
Campbell, S. J. +7 more
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Acanthamoeba castellanii induces host cell death via a phosphatidylinositol 3-kinase-dependent mechanism [PDF]
, 2005 Granulomatous amoebic encephalitis due to Acanthamoeba castellanii is a serious human infection with fatal consequences, but it is not clear how the circulating amoebae interact with the blood-brain barrier and transmigrate into the central nervous ...
S. Jayasekera +11 more
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Acanthamoeba induces cell-cycle arrest in host cells [PDF]
, 2004 Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alsam, S. +5 more
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Acanthamoeba genotype T4 from the UK and Iran and isolation of the T2 genotype from clinical isolates [PDF]
, 2005 The majority of the keratitis-causing Acanthamoeba isolates are genotype T4. In an attempt to determine whether predominance of T4 isolates in Acanthamoeba keratitis is due to greater virulence or greater prevalence of this genotype, Acanthamoeba ...
Warhurst, D. +10 more
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'Acanthamoeba' produces disseminated infection in locusts and traverses the locust blood-brain barrier to invade the central nervous system [PDF]
, 2010 BACKGROUND: Many aspects of Acanthamoeba granulomatous encephalitis remain poorly understood, including host susceptibility and chronic colonization which represent important features of the spectrum of host-pathogen interactions.
Mortazavi, Parisa Nakhostin +11 more
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Alkylphosphocholines and quaternary ammonium compounds against acanthamoeba keratitis [PDF]
, 2020 Acanthamoeba keratitis (AK) is a sight threatening infection caused by the free-living amoeba Acanthamoeba. This infection is largely associated with contact lens wear and the recent increase in AK incidences highlights the ineffectiveness of existing ...
Williams, Roderick A.M., Mooney, Ronnie
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