Results 111 to 120 of about 9,474,361 (376)

Effects of Accelerated Aging and Acid Scarification of Seed Coat with Hydrochloric Acid on Seed Germination Characteristics of Chickpea c.v. Kaka [PDF]

Ikufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2014
To evaluate the effects of accelerated aging and seed coat scarification with Hydrochloric acid (HCl) on seed germination characteristics of chickpea (Cicer arietinum) c.v.
R. Sadrabadi Haghighi
doaj  

Accelerated Aging with Electrical Overstress and Prognostics for Power MOSFETs [PDF]

, 2011
Power electronics play an increasingly important role in energy applications as part of their power converter circuits. Understanding the behavior of these devices, especially their failure modes as they age with nominal usage or sudden fault development
Celaya, Jose Ramon, Goebel, Kai F., Mahiuddin, Shompa, Saha, Sankalita, Vashchenko, Vladislav   +4 more
core   +1 more source

Aging enhances contraction to thromboxane A2 in aorta from female senescence mice [PDF]

, 2013
The time-course for aging-associated effects on vascular reactivity to U46619, a stable analogue of thromboxane A2 (TXA2), was studied in aorta from female senescence-accelerated mice-prone (SAMP8), a murine model of accelerated senescence.
Bueno, C., Dantas, A. P., Heras, Magda, Hermenegildo, Carlos, Medina Bessó, Pascual, Novella del Campo, Susana, Novensá, L., Segarra Irles, Gloria Vicenta   +7 more
core   +2 more sources

The Influence of Virus Infection on Microglia and Accelerated Brain Aging

Cells, 2021
Microglia are the resident immune cells of the central nervous system contributing substantially to health and disease. There is increasing evidence that inflammatory microglia may induce or accelerate brain aging, by interfering with physiological ...
L. Filgueira, A. Larionov, Nils Lannes
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Cerebellar Morphometry and Cognition in the Context of Chronic Alcohol Consumption and Cigarette Smoking. [PDF]

, 2020
BackgroundCerebellar atrophy (especially involving the superior-anterior cerebellar vermis) is among the most salient and clinically significant effects of chronic hazardous alcohol consumption on brain structure.
Cootes T, Fregly AR, Harper CG, Sullivan EV, Victor M, Wang X   +5 more
core   +1 more source

Obesity accelerates cardiovascular ageing

European Heart Journal
Abstract A global obesity pandemic, coupled with an increasingly ageing population, is exacerbating the burden of cardiovascular disease. Indeed, clinical and experimental evidence underscores a potential connection between obesity and ageing in the pathogenesis of various cardiovascular disorders. This is further supported by the notion
Ruperez, Celia, Madeo, Frank, de Cabo, Rafael, Kroemer, Guido, Abdellatif, Mahmoud   +4 more
openaire   +3 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

The emerging role of cellular senescence in renal diseases [PDF]

, 2020
Cellular senescence represents the state of irreversible cell cycle arrest during cell division. Cellular senescence not only plays a role in diverse biological events such as embryogenesis, tissue regeneration and repair, ageing and tumour occurrence ...
Alpini, Gianfranco, Chen, Rong, Francis, Heather, Glaser, Shannon, Li, Siwen, Li, Xuesen, Meng, Fanyin, Wan, Ying, Wu, Nan, Zhang, Chunmei, Zhou, Bingru, Zhou, Tianhao, Zou, Ping   +12 more
core   +1 more source

Cytomegalovirus infection accelerates epigenetic aging

Experimental Gerontology, 2015
Epigenetic mechanisms such as DNA methylation (DNAm) have a central role in the regulation of gene expression and thereby in cellular differentiation and tissue homeostasis. It has recently been shown that aging is associated with profound changes in DNAm. Several of these methylation changes take place in a clock-like fashion, i.e.
Jylhava Juulia, Kananen Laura, Jylha Marja, Marttila Saara, Nevalainen Tapio, Hervonen Antti, Hurme Mikko, Hurme Mikko   +7 more
openaire   +2 more sources