Results 11 to 20 of about 9,228,267 (373)
The Journal of nutrition, health and aging, 2023 The population of older adults with obesity is rapidly increasing. Through shared pathophysiologic mechanisms, obesity exacerbates the age-related decline in physical function, which leads to frailty and disability. Obesity and aging are characterized by
D. Villareal
semanticscholar +2 more sources
Progeria and accelerated cardiovascular aging
Cardiology Plus, 2018 Hutchinson–Gilford Progeria syndrome (HGPS) is characterized by accelerated aging leading to death in the teen years, usually due to severe coronary and/or carotid disease. The clinical presentation includes stunted growth, alopecia, loss of subcutaneous
Brandon K Walther +3 more
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Deletion of enzymes for de novo NAD + biosynthesis accelerated ovarian aging
Aging Cell, 2023 Recent advances highlight the pivotal role of nicotinamide adenine dinucleotide (NAD+) in ovarian aging. However, the roles of de novo NAD+ biosynthesis on ovarian aging are still unknown.
Qingling Yang +7 more
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Induction of Accelerated Aging in a Mouse Model
Cells, 2022 With the global increase of the elderly population, the improvement of the treatment for various aging-related diseases and the extension of a healthy lifespan have become some of the most important current medical issues.
N. Cai, Yifan Wu, Yan Huang
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Sickle cell disease as an accelerated aging syndrome
Experimental biology and medicine, 2022 Sickle cell disease (SCD) is characterized by vaso-occlusion, hemolysis, and systemic manifestations that form the hallmark of the disease. Apart from morbidity, SCD is also associated with increased mortality and decreased quality of life.
I. Idris +2 more
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Cancer Treatment-Induced Accelerated Aging in Cancer Survivors: Biology and Assessment
Cancers, 2021 Simple Summary Many modalities used to treat or control cancer lead to accelerated aging in cancer survivors. However, the effects of cancer treatments on aging in individuals with cancer remain poorly studied.
Shuo Wang +3 more
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Accelerated aging: A marker for social factors resulting in cardiovascular events?
SSM: Population Health, 2021 Background: Medicine and public health are shifting away from a purely “personal responsibility” model of cardiovascular disease (CVD) prevention towards a societal view targeting social and environmental conditions and how these result in disease. Given
Sarah N. Forrester +6 more
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Polymers, 2021 During their useful life, polymers are subject to degradation processes due to exposure to specific environmental conditions over long times. These processes generally lead to changes, almost always irreversible, of properties and performances of ...
M. Frigione, Á. Rodríguez-Prieto
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Failure of immunosurveillance accelerates aging [PDF]
OncoImmunology, 2019 Immunosurveillance is generally conceived as a mechanism through which the immune system detects and eliminates (pre-)malignant cells, thus reducing the risk of developing cancer. A recent paper by Ovadya et al. demonstrates that knockout of the gene coding for perforin-1 causes accelerated accumulation of senescent cells in multiple mouse organs ...
Maria Perez-Lanzon +2 more
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Obesity and accelerated epigenetic aging in a high-risk cohort of children
Scientific Reports, 2022 New insights into mechanisms linking obesity to poor health outcomes suggest a role for cellular aging pathways, casting obesity as a disease of accelerated biological aging. Although obesity has been linked to accelerated epigenetic aging in middle-aged
Laura Etzel +11 more
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