Results 41 to 50 of about 979,081 (252)
Is Schizophrenia a Syndrome of Accelerated Aging? [PDF]
Schizophrenia Bulletin, 2008 Schizophrenia is associated with a number of anatomical and physiological abnormalities outside of the brain, as well as with a decrease in average life span estimated at 20% in the United States. Some studies suggest that this increased mortality is not entirely due to associated causes such as suicide and the use of psychotropic medications.
Brian, Kirkpatrick +4 more
openaire +2 more sources
UV-accelerated aging test conditions.
, 2022 UV-accelerated aging test conditions.
Feng Chen (25347) +2 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Frontiers in EndocrinologyObjectiveTo investigate the factors influencing accelerated aging in patients with type 2 diabetes mellitus (T2DM) and coronary heart disease (CHD).MethodsA total of 216 patients diagnosed with T2DM and CHD between August 2019 and August 2023 at Xuzhou ...
Zehua Huang +4 more
doaj +1 more source
IEEE Access, 2019 In this paper, seven LED lamps are selected to investigate how the junction temperature (Tj) of LED varies during the step-stress temperature accelerated aging test. The ambient temperatures are 80 °C and 70 °C for the first and second step
Xiao-Xun Wang +4 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Association between eGDR and accelerated aging: the mediating role of ePWV
Diabetology & Metabolic SyndromeObjective This study examines the association between estimated glucose disposal rate (eGDR) and accelerated aging in middle-aged and older adults, with a focus on the mediating role of estimated pulse wave velocity (ePWV).
Shaoyan Lu +4 more
doaj +1 more source
Some molecular-genetic determinants of premature aging in women
Consilium MedicumBackground. Accelerated biological aging is associated with age-related diseases and an increased risk of mortality. Genetic predisposition may be an important factor in this process. Aim.
Elena V. Kudryavtseva +7 more
doaj +1 more source