Results 41 to 50 of about 10,649,676 (300)

Impact of Accelerated Ageing Process on Viability of Egyptian Cotton Seeds [PDF]

Journal of Plant Production, 2020
Genetic analysis was employed to investigate the influence of aging treatments on cottonseed viability and to decipher the inheritance pattern of seed quality traits (electrolyte leakage,seed imbibing %, germination % and root and shoot fresh weights ...
Doha Attia, B. Goda, Y. EL-Mansy, M. Abdel-Moneam, M. Sultan   +4 more
doaj   +1 more source

The Effects of Social Adversity, Discrimination, and Health Risk Behaviors on the Accelerated Aging of African Americans: Further Support for the Weathering Hypothesis

Social Science & Medicine (1967), 2020
BACKGROUND The weathering hypothesis views the elevated rates of illness, disability, and mortality seen among Black Americans as a physiological response to the structural barriers, material hardships, and identity threats that comprise the Black ...
R. Simons, M. Lei, Eric T. Klopack, S. Beach, F. Gibbons, R. Philibert   +5 more
semanticscholar   +1 more source

Failure of immunosurveillance accelerates aging [PDF]

OncoImmunology, 2019
Immunosurveillance is generally conceived as a mechanism through which the immune system detects and eliminates (pre-)malignant cells, thus reducing the risk of developing cancer. A recent paper by Ovadya et al. demonstrates that knockout of the gene coding for perforin-1 causes accelerated accumulation of senescent cells in multiple mouse organs ...
Maria Perez-Lanzon, Laurence Zitvogel, Guido Kroemer   +2 more
openaire   +4 more sources

Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice

Aging Cell, 2020
Senescent cells accumulate with age in vertebrates and promote aging largely through their senescence‐associated secretory phenotype (SASP). Many types of stress induce senescence, including genotoxic stress.
Matthew J. Yousefzadeh, J. Zhao, Christina Bukata, Erin A. Wade, S. McGowan, Luise A Angelini, Michael P. Bank, Aditi U. Gurkar, Collin A McGuckian, Mariah F Calubag, Jonathan I Kato, C. Burd, P. Robbins, L. Niedernhofer   +13 more
semanticscholar   +1 more source

Accelerated biological aging elevates the risk of cardiometabolic multimorbidity and mortality

Nature Cardiovascular Research
Associations of biological aging with the development and mortality of cardiometabolic multimorbidity (CMM) remain unclear. Here we conducted a multistate analysis in 341,159 adults of the UK Biobank.
M. Jiang, Sifan Tian, Shuzhen Liu, Yuting Wang, Xinbiao Guo, Tao Huang, Xihong Lin, D. Belsky, Andrea A. Baccarelli, Xu Gao   +9 more
semanticscholar   +1 more source

The relationship between serum uric acid and accelerated aging in middle-aged and older adults: a prospective cohort study based on CHARLS

The Journal of Nutrition, Health and Aging
Objective: This study seeks to determine the association between serum uric acid (SUA) and accelerated aging among middle-aged and older adults in China, as well as assess the relationship between SUA trajectories and the risk of accelerated aging ...
Weiyi Shi, Zihong Cai, Xiaoxu Ren, Juehan Wang, Hang Zhou, Zuobing Chen   +5 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Effect of Accelerated Ageing and Natural Storage on Germination, Seedling Growth and Reserves Depletion of Chickpea (Cicer arietinum) Seeds

پژوهش‌های بذر ایران, 2017
This study was conducted to evaluate the effects of accelerated aging and natural storage on seed germination and seedling heterotrophic growth of chickpea in Gorgan University of Agricultural Sciences and Natural Resources in 2014.
Mehdi Shaban, Farshid Ghaderifar, Hamidreza Sadeghipour, Ahad Yamchi   +3 more
doaj   +2 more sources

Accelerated epigenetic aging in newborns with Down syndrome

Aging Cell, 2022
Accelerated aging is a hallmark of Down syndrome (DS), with adults experiencing early‐onset Alzheimer's disease and premature aging of the skin, hair, and immune and endocrine systems.
Keren Xu, Shaobo Li, I. Muskens, N. Elliott, S. Myint, Priyatama Pandey, H. Hansen, L. Morimoto, Alice Y. Kang, Xiaomei Ma, C. Metayer, B. Mueller, I. Roberts, K. Walsh, S. Horvath, J. Wiemels, A. D. de Smith   +16 more
semanticscholar   +1 more source

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell   +19 more
wiley   +1 more source