Results 81 to 90 of about 10,649,676 (300)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Media use and well-being in older adults: The mediating role of social inclusion and subjective accelerated aging

International Psychogeriatrics
Aims: With the rise in global life expectancy, interest in older adults’ mental well-being is growing. Media use is currently seen as potentially contributing to well-being.
Naama Nebenzahl-Elitzur, MSW, Maya Kagan, Professor, Ester Zychlinski, Professor   +2 more
doaj   +1 more source

Accelerated aging test to evaluate of physiological potential in coriander seeds

Semina: Ciências Agrárias, 2015
The vigor tests are essential in programs of quality control of seeds, and the accelerated aging test is one which can be used for this purpose. In this sense, this paper aimed to study the methodology of the accelerated aging test, in order to identify ...
Maria Francisca Soares Pereira , Salvador Barros Torres , Paulo César Ferreira Linhares   +2 more
doaj   +1 more source

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1−/Δ7 mice

Immunity & Ageing, 2019
The use of Akkermansia muciniphila as potential therapeutic intervention is receiving increasing attention. Health benefits attributed to this bacterium include an improvement of metabolic disorders and exerting anti-inflammatory effects.
B. van der Lugt, A. V. Van Beek, S. Aalvink, B. Meijer, B. Sovran, W. Vermeij, Renata M. C. Brandt, W. D. de Vos, H. Savelkoul, W. Steegenga, C. Belzer   +10 more
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Obesity accelerates thymic aging

Blood, 2009
Abstract As the expanding obese population grows older, their successful immunologic aging will be critical to enhancing the health span. Obesity increases risk of infections and cancer, suggesting adverse effects on immune surveillance.
Hyunwon, Yang, Yun-Hee, Youm, Bolormaa, Vandanmagsar, Jennifer, Rood, K Ganesh, Kumar, Andrew A, Butler, Vishwa Deep, Dixit   +6 more
openaire   +3 more sources

Anxiety disorders and accelerated cellular ageing [PDF]

British Journal of Psychiatry, 2015
BackgroundAnxiety disorders increase the risk of onset of several ageing-related somatic conditions, which might be the consequence of accelerated cellular ageing.AimsTo examine the association between anxiety status and leukocyte telomere length (LTL) as an indicator of cellular ageing.MethodData are from individuals with current (n = 1283) and ...
Verhoeven, Josine E., Revesz, Dora, van Oppen, Patricia, Epel, Elissa S., Wolkowitz, Owen M., Penninx, Brenda W.   +5 more
openaire   +4 more sources

Interpretable machine learning with SHAP analysis identifies redox-modulating dietary antioxidants for predicting accelerated biological aging

Experimental Gerontology
Background: Aging is a complex biological process characterized by progressive functional decline across multiple physiological systems, and biological age provides a more accurate reflection of an individual's aging status than chronological age ...
Bei Zhang, Xinyu Zhang, Lanyue Ma, Danfei Li, Yijia Li, Sen Lin, Lisheng Peng, Li He   +7 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Effects of Accelerated Aging and Acid Scarification of Seed Coat with Hydrochloric Acid on Seed Germination Characteristics of Chickpea c.v. Kaka [PDF]

Ikufīziyuluzhī-i Giyāhān-i Zirā̒ī, 2014
To evaluate the effects of accelerated aging and seed coat scarification with Hydrochloric acid (HCl) on seed germination characteristics of chickpea (Cicer arietinum) c.v.
R. Sadrabadi Haghighi
doaj