Results 71 to 80 of about 979,081 (252)

Effect of radiant exposure and UV accelerated aging on physico-chemical and mechanical properties of composite resins

Journal of Applied Oral Science, 2019
Currently, there is no consensus in terms of defining the minimum radiant exposure values necessary for achieving adequate properties of composite resin. In addition, the long-term influence that radiant exposure has on the properties of composite resins
Carlos Enrique Cuevas-Suárez, Carine Tais Walter Meereis, Norma D’accorso, Ricardo Macchi, Adriana Leticia Ancona-Meza, Eliezer Zamarripa-Calderón   +5 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Other title: [Kansas Department on Aging Overview]

, 2009
application/pdf; "February 17, 2009."; Presentation before the Kansas Legislature, House Social Services Subcommittee on the Kansas Department on Aging, by Secretary Kathy Greenlee, Kansas Department on Aging.Presentation discussing the Governor's budget
Greenlee, Kathy.
core   +1 more source

Obesity accelerates thymic aging

Blood, 2009
Abstract As the expanding obese population grows older, their successful immunologic aging will be critical to enhancing the health span. Obesity increases risk of infections and cancer, suggesting adverse effects on immune surveillance.
Hyunwon, Yang, Yun-Hee, Youm, Bolormaa, Vandanmagsar, Jennifer, Rood, K Ganesh, Kumar, Andrew A, Butler, Vishwa Deep, Dixit   +6 more
openaire   +3 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

The role of health behaviors in links between stress and epigenetic aging

Brain, Behavior, & Immunity - Health
High levels of stress are associated with accelerated epigenetic aging and health risks. However, less is known about the independent effects of different types of stress and whether these effects are explained by unhealthy behaviors. This study involved
Marlon Goering, Kyle J. Bourassa, Maxine Weinstein, Anthony P. Auger, Casey K. Brown   +4 more
doaj   +1 more source

Other title: Kansas State Advisory Council on Aging report for fiscal years--Other title: Kansas Advisory Council on Aging annual report

, 1979
The reports were prepared with the assistance of the Kansas Department on Aging.; Created in 1977 by the Kansas Act on the Aging, the ACA is represents different geographical, social and ethnic groups, with at least half its members being 60 years of age
Kansas Advisory Council on Aging.
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source