Results 191 to 200 of about 159,613 (271)

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

Spending by the Centers for Medicare & Medicaid Services Before and After Confirmation of Benefit for Drugs Granted US Food and Drug Administration Accelerated Approval, 2012 to 2017.

JAMA Health Forum, 2022
Skydel JJ, Egilman AC, Wallach JD, Ramachandran R, Gupta R, Ross JS.   +5 more
europepmc   +1 more source

Synergistic Fluorine and Cyanide Co‐Modification to Reinforce Photoinduced Excitons Formation and Transfer for Efficient CO2 Photoreduction

Advanced Functional Materials, EarlyView.
An advanced F‐doped and ─CN group co‐modified FCCN is developed. Due to the synergistic effects of co‐modification in promoting photogenerated exciton generation, enhancing charge kinetics, expanding active interfacial areas, and optimizing CO2 interfacial reactions, the FCCN photocatalyst demonstrates excellent catalytic performance and high ...
Sheng‐Qi Guo, Qingqing Dong, Xiaodong Sun, Ziqi Zhang, Linda Wang, Lei Bao, Bozhan Li, Hui Li, Yanrui Li, Tianyi Ma   +9 more
wiley   +1 more source

Assessment of Coverage in England of Cancer Drugs Qualifying for US Food and Drug Administration Accelerated Approval.

JAMA Intern Med, 2021
Cherla A, Naci H, Kesselheim AS, Gyawali B, Mossialos E.   +4 more
europepmc   +1 more source

Reconfigurable Magnetic Soft Microrobot for Acoustically Triggered Targeted Bacterial Sterilization

Advanced Functional Materials, EarlyView.
Reconfigurable magnetic soft microrobots integrate in situ‐grown piezoelectric zinc oxide nanorods that produce reactive oxygen species upon acoustic excitation. Combining magnetically guided transport with thermally induced planar reconfiguration, the microrobots achieve targeted delivery and enhanced bacterial sterilization through efficient on ...
Quan Gao, Fan Li, Jiajie Gao, Elric Zhang, Yingdong Su, Ni Qin, Hao Ye, Josep Puigmartí, Giuseppe Cantarella, Simone Schuerle, Jiang Wu, Bradley J. Nelson, Salvador Pané   +12 more
wiley   +1 more source

Estimated Medicare Spending on Cancer Drug Indications With a Confirmed Lack of Clinical Benefit After US Food and Drug Administration Accelerated Approval.

JAMA Intern Med, 2021
Shahzad M, Naci H, Wagner AK.
europepmc   +1 more source

Thermoplasmonic Nanorings for Passive Solar‐Responsive Smart Windows in Energy‐Efficient Building Applications

Advanced Functional Materials, EarlyView.
This work presents scalable silver nanorings with tunable thermoplasmonic properties for smart window applications. By responding to sunlight and environmental changes, the nanorings modulate near‐infrared light and reduce heat transmission. Their unique geometry enables dynamic optical control, offering a promising route toward energy‐efficient ...
Xavier Baami González, Duncan S. Sutherland   +1 more
wiley   +1 more source

Factors in Time to Full Approval or Withdrawal for Anticancer Medicines Granted Accelerated Approval by the FDA.

JAMA Netw Open
Tibau A, Hwang TJ, Romano A, Borrell M, Gich I, Molto C, Kesselheim AS.   +6 more
europepmc   +1 more source

Comparison of Duration of Postapproval vs Pivotal Trials for Therapeutic Agents Granted US Food and Drug Administration Accelerated Approval, 2009-2018.

JAMA Netw Open, 2021
Wallach JD, Ramachandran R, Bruckner T, Ross JS.   +3 more
europepmc   +1 more source

Elamipretide: The first cardiolipin-directed mitochondrial therapeutic for Barth syndrome approved under accelerated approval

Chenru Zhao, Xuemei Zhuang, Jianjun Gao
openalex   +2 more sources