Results 41 to 50 of about 486,445 (234)

Numerical Simulation of Non-Stationary Parameter Creep Large Deformation Mechanism of Deep Soft Rock Tunnel

open access: yesApplied Sciences, 2022
The accelerated creep plays an important role in the disasters of soft-rock tunnels under high stress. However, most of previous studies only involved attenuation creep and uniform creep.
Jiancong Xu   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Review of Creep Cavitation and Rupture of Low Cr Alloy and its Weldment [PDF]

open access: yes, 2013
This paper presents a review of creep cavitation and rupture of low Cr alloy and its weldment, particular in the heat-affected zone (HAZ). Creep damage is one of the serious problems for the high temperature industry.
Xu, Qiang   +6 more
core   +1 more source

Energy-based nonlinear damage creep model considering the influence of the concrete creep rate

open access: yesFrontiers in Materials
In order to study the influence of confining pressure on the deformation of concrete, triaxial compression and creep tests under different confining pressures are carried out using a combination of laboratory tests and theoretical analysis.
Lu Wang
doaj   +1 more source

Undrained creep behavior of CO2 hydrate-bearing sand and its constitutive modeling considering the cementing effect of hydrates

open access: yesSoils and Foundations, 2022
A technique for carbon dioxide (CO2) capture and storage using CO2 hydrates where CO2 is stored as solid hydrates in the seabed ground, is attracting attention.
Masaki Yoshimoto, Sayuri Kimoto
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Development of Advanced Creep Damage Constitutive Equations for Low CR Alloy Under Long-Term Service [PDF]

open access: yes
Low Cr alloys are mostly utilized in structural components such as steam pipes, turbine generators and reactor pumps operating at high temperatures from 400℃ to 700℃ in nuclear power plants.
Xu, Qihua
core   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Performance and Life Assessment of Reformer Tubes in Petrochemical Industries

open access: yesHigh Temperature Materials and Processes, 2014
High temperature mechanical properties of service exposed reformer tubes are compared and revalidated with those of virgin material for the sake of health assessment studies.
Raj A.   +5 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

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