Results 101 to 110 of about 265,739 (284)

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

Central versus paracentral cone location and outcomes of accelerated cross-linking in keratoconus patients. [PDF]

open access: yesEye (Lond), 2021
Mimouni M   +5 more
europepmc   +1 more source

Magnetic explosions: role of the inductive electric field

open access: yes, 2012
Inclusion of the inductive electric field, ${\bf E}_{\rm ind}$ due to the temporally changing ${\bf B}$, in magnetic explosions is discussed, with emphasis on solar flares. Several roles played by ${\bf E}_{\rm ind}$ are identified: on a global scale, ${\
Melrose, D. B.
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Different accelerated corneal collagen cross-linking treatment modalities in progressive keratoconus

open access: yesEye and Vision, 2019
Background To compare the outcomes of two different protocols of accelerated corneal crosslinking (CXL) on visual, corneal high order aberrations (HOA) and topographic parameters in patients with progressive keratoconus.
Ahmet Kirgiz   +2 more
doaj   +1 more source

Use of water-based carbonyl-functional polymers on a cross-linker-free highperformance leather finish [PDF]

open access: yes, 2011
The present paper aims to study a new high-performance coating formulation while avoiding the use of cross-linkers. By using acrylic polymers with carbonyl functional groups, the negative environmental effects of the finishing process can be minimized ...
Bacardit Dalmases, Anna   +4 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

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