Results 71 to 80 of about 519,139 (282)

Accelerated Degradation Model of Nonlinear Wiener Process Based on Fixed Time Index

Mathematics, 2019
In the process of extrapolating a lifetime distribution function under normal storage conditions through nonlinear accelerated degradation data, time indexes under the normal storage conditions are usually set to the mean value of time indexes under ...
Hanzhong Liu, Jiacai Huang, Yuanhong Guan, Li Sun   +3 more
doaj   +1 more source

Accelerated Rates Regression Models for Recurrent Failure Time Data [PDF]

Lifetime Data Analysis, 2004
In this article, we formulate a semiparametric model for counting processes in which the effect of covariates is to transform the time scale for a baseline rate function. We assume an arbitrary dependence structure for the counting process and propose a class of estimating equations for the regression parameters. Asymptotic results for these estimators
openaire   +3 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The accelerated failure time regression model under the extended-exponential distribution with survival analysis

AIMS Mathematics
In this paper, we propose a parametric accelerated failure time (AFT) hazard-based regression model with the extended alpha-power exponential (EAPE) baseline distribution.
Veronica Kariuki, Anthony Wanjoya , Oscar Ngesa, Mahmoud M. Mansour, Enayat M. Abd Elrazik, Ahmed Z. Afify   +5 more
doaj   +1 more source

Survival analysis for motorcycle usage time in work-tours

International Journal of Transportation Science and Technology, 2020
The aim of this paper is to identify effective factors on motorcycle usage time in work-tours. To do so, a survey on motorcyclists whose workplaces are in the Central Business District (CBD) of Tehran is conducted.
Amir Bahador Parsa, Arsham Bakhtiari, Meeghat Habibian, Abolfazl (Kouros) Mohammadian   +3 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Disease progression of cancer patients during COVID-19 pandemic: a comprehensive analytical strategy by time-dependent modelling

BMC Medical Research Methodology, 2020
Background As the whole world is experiencing the cascading effect of a new pandemic, almost every aspect of modern life has been disrupted. Because of health emergencies during this period, widespread fear has resulted in compromised patient safety ...
Atanu Bhattacharjee, Gajendra K. Vishwakarma, Souvik Banerjee, Sharvari Shukla   +3 more
doaj   +1 more source

Survival Chances of Start-Ups - do Regional Conditions Matter? [PDF]

, 2005
This paper analyses the effect of industry, regional and firm level characteristics on the post entry performance of newly founded businesses by means of an econometric survival time model.
Falck, Oliver
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