Results 51 to 60 of about 1,219,708 (305)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Chinese Journal of Mechanical Engineering, 2018 Constant stress accelerated life tests (ALTs) can be applied to obtain a high estimation accuracy of reliability measurements, but these are time-consuming tests. Progressive stress ALTs can yield failures more quickly but cannot guarantee the estimation
Wen-Hua Chen +4 more
doaj +1 more source
Degradation Characteristics and Reliability Assessment of 1310 nm VCSEL for Microwave Photonic Link
Applied Sciences, 2022 The long-term reliability of the commercially available vertical-cavity surface-emitting laser (VCSEL) at 1310 nm wavelength is investigated. To do so, a high current accelerated life test is used to evaluate the 1310 nm VCSEL reliability.
Wenyuan Liao +7 more
doaj +1 more source
Design of Accelerated Life Test Plans—Overview and Prospect
, 2018 Accelerated life test (ALT) is currently the main method of assessing product reliability rapidly, and the design of efficient test plans is a critical step to ensure that ALTs can assess the product reliability accurately, quickly, and economically ...
Wenhua Chen +4 more
semanticscholar +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Accelerated Life Test and Life Analysis of Self-lubricating Radial Spherical Plain Bearing
Jixie chuandong, 2016 With life testing machine developed on our own,according to data terminated life test method without substitution,the accelerated life tests for a certain type of self- lubricating radial spherical plain bearing are carried out.
Lu Jianjun, Qiu Ming, Li Yingchun
doaj
A Study on the Accelerated Life Test of Axle Bearing for Railway Vehicles Using Rotational Speed-Temperature Variation Curve [PDF]
한국정밀공학회지, 2017 Domestic railway-maintenance technologies have been developed over more than 100 years of railway operation. Based on these technologies, we are striving to localize the vehicular parts, while the component localization is currently from 90-95%.
Jae Won Lee +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source