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Mechanisms of Treatment Failure
1993The recently published overview of systemic treatment of patients with early breast cancer provides the best information available concerning the impact of these treatments on disease-free and overall survival [4] (reprinted in part in this volume). The modest reduction in risk of relapse achieved by these treatments may translate into major community ...
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Mechanisms for Cachexia in Heart Failure
Current Heart Failure Reports, 2013The combination of profound muscle wasting and severe weight loss that occurs in heart failure is a complex phenomenon that involves the interplay of numerous factors. In this article, we describe processes that contribute to cachexia, as part of the clinical sequelae of heart failure, and their potential underlying mechanisms.
Vincent, Pureza, Viorel G, Florea
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2016
This chapter will review the concepts of fracture and fatigue that occupy most of part failures in mechanical system subjected to random stress (or loads). To figure out the mechanical system failures, it will benefit engineer to design the product structures—automobile, bridge, skyscrapers, and the others—in the allowable stress and strain as ...
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This chapter will review the concepts of fracture and fatigue that occupy most of part failures in mechanical system subjected to random stress (or loads). To figure out the mechanical system failures, it will benefit engineer to design the product structures—automobile, bridge, skyscrapers, and the others—in the allowable stress and strain as ...
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Failure mechanisms in fibrous scaffolds
Acta Biomaterialia, 2013Polymeric fibrous scaffolds have been considered as replacements for load-bearing soft tissues, because of their ability to mimic the microstructure of natural tissues. Poor toughness of fibrous materials results in failure, which is an issue of importance to both engineering and medical practice.
C T, Koh +3 more
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Time-To-Failure Models for Selected Failure Mechanisms in Mechanical Engineering
2010The mechanical properties of materials are related to the fundamental bonding strengths of the constituent atoms in the solid and any bonding defects which might form. A molecular model is presented so that primary bond formation mechanisms (ionic, covalent, and metallic) can be better understood.
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Illness: A mechanism for coping with failure
Social Science & Medicine (1967), 1973Abstract Illness represents one way of coping with failure and the physician plays a unique role as the sole authority granting legitimation for the sick role. For people of limited means or incomplete knowledge of and access to other medical alternatives, the neighborhood clinic, when it is free and accessible, may serve as the major locus for ...
Judith T. Shuval +2 more
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Mechanisms of Failure of Modular Prostheses
Clinical Orthopaedics and Related Research, 1992The expectations of wear and longevity of total hip components are based in large part on Charnley's early work. The evolution of the total hip from the one-piece, all-polyethylene acetabular component and fixed-head femoral component to the myriad of parts that comprise many of today's total hip designs has brought with it an array of potential ...
J P, Collier +6 more
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Mechanisms of Arrhythmias in Heart Failure
Journal of Cardiovascular Electrophysiology, 1998Mechanisms of Arrhythmias in Heart Failure. The diagnosis of heart failure infers a bad prognosis. Mortality is high and many patients die suddenly. Ventricular arrhythmias, commonly observed in patients with heart failure, are thought to underlie at least some of these sudden deaths.
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Mechanical failure of solid polymers
Uspekhi Fizicheskih Nauk, 1964TABLE OF CONTENTS I. Some ideas on failure in solids 401 II. Experimental studies of failure of solid polymers 402 1. Test of the applicability of Griffith's method 402 2. Time-dependence of the strength of polymers 404 3. The relation between the laws of failure and deformation 407 4.
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Update on Mechanisms of Ultrafiltration Failure
Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 2009Ultrafiltration failure (UFF) continues to be a major complication of peritoneal dialysis (PD), particularly long-term PD. Continuous exposure to bioincompatible PD solutions causes inflammation of the peritoneal membrane, which progressively undergoes fibrosis and angiogenesis and, ultimately, UFF.
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