Results 41 to 50 of about 12,735,996 (314)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Due to the periodic changes of water supply and temperature in canals in high cold regions, the canal soils will undergo the "wetting-drying and freeze-thaw" cycles, which will aggravate the uncoordinated deformation of the heightening canals.
GUO Wan-li 1, 2, CAI Zheng-yin 1, 2, WANG Yi 3, HUANG Ying-hao 1, 2, ZHANG Chen 2
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Experimental study on hydraulic fracture of gravelly soil core
The hydraulic fracture tests on two kinds of graded gravelly soils are carried out by using the improved triaxial apparatus. For the hydraulic fracture pressures on the gravelly soils, the soil properties and confining pressure are the key influence ...
LING Hua 1, 2, WANG Wei 3, WANG Fang 1, 2, FU Hua 1, 2, HAN Hua-qiang 1, 2
doaj +1 more source
Fatigue failure mechanism analysis of 1Cr17Ni2 stainless steel blades ground by an abrasive belt
Fatigue failure, as the main failure form of aero-engine blades, has a direct impact on the reliability and service life of aviation equipment. In order to improve the service performance of machined blades, it is necessary to understand the failure ...
Mei Zhang +3 more
doaj +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The field observations show that the existing widely-used constitutive models tend to underestimate the settlement of dams higher than 200 m. One of the main reasons is the separation of load-induced deformation and creep in such models and the ...
CHEN Sheng-shui 1,2, FU Zhong-zhi 1,2, SHI Bei-xiao 1, YUAN Jing 3
doaj +1 more source
Influences of vertical drainage wells on stability of expansive soil canals in North Xinjiang
The water conveyance canal in North Xinjiang is a periodic water supply canal, and the "wetting-drying" circulation caused by canal water leakage may significantly reduce the strength of expansive soils and further affect the stability of the expansive ...
DENG Ming-jiang 1, CAI Zheng-yin 2, 3, GUO Wan-li 3, HUANG Ying-hao 2, 3, ZHANG Chen 3
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Failure analysis of chopped carbon fiber SMC composites by micro X-ray computed tomography
The complex internal three-dimensional fiber distributions and the various microcrack propagation processes of the chopped carbon fiber sheet molding compound (SMC) composites aggravate the difficulty of failure analysis.
CHENG Zijing +2 more
doaj +1 more source

