Results 31 to 40 of about 965,338 (266)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Numerical simulation of evolution of viscous debris flows considering interface

Yantu gongcheng xuebao, 2019
Based on the interface theory, taking the corresponding surface of the yielding depth of debris flows as the interface, the viscous debris flow can be divided into ideal fluid and Bingham fluid.
DENG Zhao 1, CHEN Sheng-shui 1, 2, ZHONG Qi-ming 1, 2
doaj   +1 more source

Influences of filling replacement and drainage modification on stability of water conveyance canals in North Xinjiang

Yantu gongcheng xuebao, 2021
The leakage of canals in North Xinjiang is serious, and the behavior of expansive canal soil deteriorates rapidly, leading to frequent canal slides. In order to solve this problem, the canals are refilled and rebuilt, and a drainage system is set up at ...
DENG Ming-jiang 1, CAI Zheng-yin 2, 3, GUO Wan-li 3, HUANG Ying-hao 2, 3, ZHANG Chen 3
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Experimental study on special physical and mechanical properties of white sandstone in North Xinjiang

Yantu gongcheng xuebao, 2020
The white sandstone is a commonly used soil material in the Gobi canal. In order to study its physical and mechanical properties, a series of indoor tests are carried out.
DENG Ming-jiang 1, CAI Zheng-yin 2, 3, GUO Wan-li 3, HUANG Ying-hao 2, 3, ZHANG Chen 3
doaj   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Experimental study on permeability and its influencing factors for sandy gravel of Dashixia dam

Yantu gongcheng xuebao, 2019
A super-large cubic permeability meter (1000 mm×1000 mm) and a traditional cylindrical large-scale permeability meter (Φ300 mm) are used to conduct systematic experiments on the permeability characteristics of gravel materials to be used in Dashixia ...
CHEN Sheng-shui 1,2, LING Hua 1,2, MI Zhan Kuang 1,2, MIAO Zhe 3, MEI Shi-ang 1,2
doaj   +1 more source

Metabolic Mechanisms in Heart Failure [PDF]

Circulation, 2007
Although neurohumoral antagonism has successfully reduced heart failure morbidity and mortality, the residual disability and death rate remains unacceptably high. Though abnormalities of myocardial metabolism are associated with heart failure, recent data suggest that heart failure may itself promote metabolic changes such as insulin resistance, in ...
Ashrafian, Houman, Frenneaux, Michael P, Opie, Lionel H   +2 more
openaire   +4 more sources

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Secretory Phospholipase A2 in Patients With Sickle Cell Disease Hospitalized for Vaso‐Occlusive Pain Episodes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Secretory phospholipase A2 (sPLA2) is an inflammatory mediator linked to acute chest syndrome (ACS) in sickle cell disease (SCD), a serious complication that can develop during an acute vaso‐occlusive pain episode (VOE). Plasma sPLA2 levels have been proposed as a potential biomarker for predicting ACS onset.
Rawan Korman, Maria Yasmine, Dunia Hatabah, Noor Alzraikat, Frank Harris, Lou Ann Brown, Satheesh Chonat, Nitya Bakshi, Chris A. Rees, Carlton Dampier, Claudia R. Morris   +10 more
wiley   +1 more source